Hypoxia is an important feature of the tumor microenvironment, and is closely associated
with cell proliferation, angiogenesis, metabolism and the tumor immune response. All these …

Synovial proliferation, neovascularization and leukocyte extravasation transform the
normally acellular synovium into an invasive tumour-like'pannus'. The highly dysregulated …

Tumor‐associated macrophages (TAMs) are recognized as antitumor suppressors, but how
TAMs behave in the hypoxic environment of hepatocellular carcinoma (HCC) remains …

Macrophages (Mf) are a heterogeneous population of tissue-resident professional
phagocytes and a major component of the leukocyte infiltrate at sites of inflammation …

Bio‐hybrid technologies aim to replicate the unique capabilities of biological systems that
could surpass advanced artificial technologies. Soft bio‐hybrid robots consist of synthetic …

Hypoxia is one of the hallmarks of the tumour microenvironment. It is the result of insufficient
blood supply to support proliferating tumour cells. In response to hypoxia, the cellular …

In the tumour microenvironment, cancer cells directly interact with both the immune system
and the stroma. It is firmly established that the immune system, historically believed to be a …

Myeloid cells in the tumor microenvironment (TME) can exist in immunosuppressive and
immunostimulatory states that impede or promote antitumor immunity, respectively. Blocking …

Hypoxia, which characterizes most tumor tissues, can alter the function of different immune
cell types, favoring tumor escape mechanisms. In this study, we show that hypoxia …

Triggering receptor expressed on myeloid cells-1 (TREM-1) is a member of the
immunoglobulin superfamily and is mainly expressed on the surface of myeloid cells such …