Escherichia coli is a remarkable and diverse organism. This normally harmless commensal
needs only to acquire a combination of mobile genetic elements to become a highly adapted …

Serine proteases exist in eukaryotic and prokaryotic organisms and have emerged during
evolution as the most abundant and functionally diverse group. In Gram-negative bacteria …

Nanoparticle physicochemical properties such as surface charge are considered to play an
important role in cellular uptake and particle–cell interactions. In order to systematically …

Until now, a common feature that defines the enteroaggregative Escherichia coli (EAEC)
strains is the ability to produce a 'stacked-brick'appearance on epithelial cells, but it does not …

In May 2011, an outbreak caused by Escherichia coli of serotype O104: H4 spread
throughout Germany (1). The next month, France also reported a cluster of E. coli O104: H4 …

Serine Protease Autotransporters of Enterobacteriaceae (SPATEs) constitute a large family
of proteases secreted by Escherichia coli and Shigella. SPATEs exhibit two distinct …

Serine protease autotransporters of Enterobacteriaceae (SPATE) constitute a superfamily of
virulence factors, resembling the trypsin‐like superfamily of serine proteases. SPATEs …

Following an infectious challenge, macrophages have to be activated in order to allow
efficient clearance of infectious pathogens, but how macrophage activation is coupled to …

Enteroaggregative Escherichia coli (EAEC) is an emerging pathogen associated with acute
and persistent diarrhea in children and adults. EAEC strains are very heterogeneous and …

Plasmid-encoded toxin (Pet) is an autotransporter protein of the serine protease
autotransporters of Enterobacteriaceae (SPATE) family, important in the pathogenicity of …