Image‐guided surgery in cancer: A strategy to reduce incidence of positive surgical margins

KR Tringale, J Pang, QT Nguyen - … Reviews: Systems Biology …, 2018 - Wiley Online Library
Primary treatment for many solid cancers includes surgical excision or radiation therapy,
with or without the use of adjuvant therapy. This can include the addition of radiation and …

[HTML][HTML] Prognostic importance of circumferential resection margin in the era of evolving surgical and multidisciplinary treatment of rectal cancer: A systematic review …

R Detering, MLW Rutgers, WA Bemelman, R Hompes… - Surgery, 2021 - Elsevier
Background Circumferential resection margin is considered an important prognostic
parameter after rectal cancer surgery, but its impact might have changed because of …

Safety and effectiveness of SGM-101, a fluorescent antibody targeting carcinoembryonic antigen, for intraoperative detection of colorectal cancer: a dose-escalation …

LSF Boogerd, CES Hoogstins, DP Schaap… - The Lancet …, 2018 - thelancet.com
Background Tumour-targeted fluorescence imaging has the potential to advance current
practice of oncological surgery by selectively highlighting malignant tissue during surgery …

Raman spectroscopy for rapid intra-operative margin analysis of surgically excised tumour specimens

TJE Hubbard, A Shore, N Stone - Analyst, 2019 - pubs.rsc.org
Raman spectroscopy, a form of vibrational spectroscopy, has the ability to provide sensitive
and specific biochemical analysis of tissue. This review article provides an in-depth analysis …

Postoperative chemotherapy improves survival in patients with resected high‐risk Stage II colorectal cancer: results of a systematic review and meta‐analysis

C Simillis, H Singh, T Afxentiou, S Mills… - Colorectal …, 2020 - Wiley Online Library
Aim The aim was to assess the benefit of adjuvant chemotherapy in high‐risk Stage II
colorectal cancer. Method A systematic literature review and meta‐analysis was performed …

Risk factors associated with circumferential resection margin positivity in rectal cancer: a binational registry study

SK Warrier, JC Kong, GR Guerra… - Diseases of the Colon …, 2018 - journals.lww.com
BACKGROUND: Rectal cancer outcomes have improved with the adoption of a
multidisciplinary model of care. However, there is a spectrum of quality when viewed from a …

Fluorescent‐guided surgery for sentinel lymph node detection in gastric cancer and carcinoembryonic antigen targeted fluorescent‐guided surgery in colorectal and …

FA Vuijk, DE Hilling, JSD Mieog… - Journal of surgical …, 2018 - Wiley Online Library
Sentinel lymph node procedures for gastric cancer resections using indocyanine green
(ICG) linked to Nanocoll outperformed normal ICG but did not provide information on …

Detection of micrometastases using SPECT/fluorescence dual-modality imaging in a CEA-expressing tumor model

MCH Hekman, M Rijpkema, DL Bos… - Journal of Nuclear …, 2017 - jnm.snmjournals.org
Intraoperative dual-modality imaging can help the surgeon distinguish tumor from normal
tissue. This technique may prove particularly valuable if small tumors need to be removed …

Defining and predicting early recurrence in patients with locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy

Z Zheng, X Wang, Y Huang, X Lu, Z Huang… - European Journal of …, 2020 - Elsevier
Background The definition of “early recurrence (ER)” after rectal cancer surgery is currently
unclear. Objective To determine an evidence-based cut-off to distinguish early and late …

Impact of specific modes of circumferential resection margin involvement in rectal cancer local recurrence: a retrospective study

J Suárez, A Goicoetxea, ML Gomez… - Journal of Surgical …, 2018 - Wiley Online Library
Purpose To compare the local recurrence rate and overall survival between patients with
circumferential resection margin (CRM) involvement by direct tumor spread and by a tumor …