Pathogenesis of acute respiratory distress syndrome

LA Huppert, MA Matthay… - Seminars in respiratory and …, 2019 - thieme-connect.com
Acute respiratory distress syndrome (ARDS) is a syndrome of acute respiratory failure
caused by noncardiogenic pulmonary edema. Despite five decades of basic and clinical …

Epigenetic underpinnings of inflammation: Connecting the dots between pulmonary diseases, lung cancer and COVID-19

S Ahmad, S Manzoor, S Siddiqui, N Mariappan… - Seminars in cancer …, 2022 - Elsevier
Inflammation is an essential component of several respiratory diseases, such as chronic
obstructive pulmonary disease (COPD), asthma and acute respiratory distress syndrome …

Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo

MCW Chan, DIT Kuok, CYH Leung, KPY Hui… - Proceedings of the …, 2016 - pnas.org
Influenza can cause acute lung injury. Because immune responses often play a role,
antivirals may not ensure a successful outcome. To identify pathogenic mechanisms and …

The acute respiratory distress syndrome: mechanisms and perspective therapeutic approaches

JN Gonzales, R Lucas, AD Verin - Austin journal of vascular …, 2015 - pmc.ncbi.nlm.nih.gov
Acute Respiratory Distress Syndrome (ARDS) is a severe lung inflammatory disorder with a
30–50% mortality. Sepsis and pneumonia are the leading causes of ARDS. On the cellular …

Cardiogenic pulmonary edema in emergency medicine

C Zanza, F Saglietti, M Tesauro, Y Longhitano… - … in Respiratory Medicine, 2023 - mdpi.com
Highlights What are the main findings? Cardiogenic pulmonary edema is the most common
cause of respiratory failure and results from increased cardiac filling pressure and alveolar …

Regulators of endothelial and epithelial barrier integrity and function in acute lung injury

R Lucas, AD Verin, SM Black, JD Catravas - Biochemical pharmacology, 2009 - Elsevier
Permeability edema is a life-threatening complication accompanying acute lung injury (ALI),
severe pneumonia and the acute respiratory distress syndrome (ARDS), which can be …

Alveolar Fluid Clearance in Pathologically Relevant Conditions: In Vitro and In Vivo Models of Acute Respiratory Distress Syndrome

LA Huppert, MA Matthay - Frontiers in Immunology, 2017 - frontiersin.org
Critically ill patients with respiratory failure from acute respiratory distress syndrome (ARDS)
have reduced ability to clear alveolar edema fluid. This reduction in alveolar fluid clearance …

Changes in ion transport in inflammatory disease

M Eisenhut - Journal of inflammation, 2006 - Springer
Ion transport is essential for maintenance of transmembranous and transcellular electric
potential, fluid transport and cellular volume. Disturbance of ion transport has been …

Mechanisms of impaired alveolar fluid clearance

H Taenaka, MA Matthay - The Anatomical Record, 2023 - Wiley Online Library
Impaired alveolar fluid clearance (AFC) is an important cause of alveolar edema fluid
accumulation in patients with acute respiratory distress syndrome (ARDS). Alveolar edema …

[HTML][HTML] Control of chemokine gradients by the retinal pigment epithelium

G Shi, A Maminishkis, T Banzon… - … & visual science, 2008 - jov.arvojournals.org
purpose. Proinflammatory cytokines in degenerative diseases can lead to the loss of normal
physiology and the destruction of surrounding tissues. In the present study, the physiological …