Fibrosis: from mechanisms to medicines

NC Henderson, F Rieder, TA Wynn - Nature, 2020 - nature.com
Fibrosis can affect any organ and is responsible for up to 45% of all deaths in the
industrialized world. It has long been thought to be relentlessly progressive and irreversible …

Revisiting fibrosis in inflammatory bowel disease: the gut thickens

S D'Alessio, F Ungaro, D Noviello, S Lovisa… - Nature Reviews …, 2022 - nature.com
Intestinal fibrosis, which is usually the consequence of chronic inflammation, is a common
complication of inflammatory bowel disease (IBD), including Crohn's disease and ulcerative …

Recent advances in clinical practice: advances in cross-sectional imaging in inflammatory bowel disease

J Rimola, J Torres, S Kumar, SA Taylor, T Kucharzik - Gut, 2022 - gut.bmj.com
Endoscopy remains the reference standard for the diagnosis and assessment of patients
with inflammatory bowel disease (IBD), but it has several important limitations. Cross …

A global consensus on the definitions, diagnosis and management of fibrostenosing small bowel Crohn's disease in clinical practice

D Bettenworth, ME Baker, JG Fletcher… - Nature Reviews …, 2024 - nature.com
Fibrostenosis of the small bowel is common in patients with Crohn's disease. No consensus
recommendations on definition, diagnosis and management in clinical practice are currently …

Assessment of Crohn's disease-associated small bowel strictures and fibrosis on cross-sectional imaging: a systematic review

D Bettenworth, A Bokemeyer, M Baker, R Mao… - Gut, 2019 - gut.bmj.com
Patients with Crohn's disease commonly develop ileal and less commonly colonic strictures,
containing various degrees of inflammation and fibrosis. While predominantly inflammatory …

Imbalance of the renin–angiotensin system may contribute to inflammation and fibrosis in IBD: a novel therapeutic target?

M Garg, SG Royce, C Tikellis, C Shallue, D Batu… - Gut, 2020 - gut.bmj.com
Objective We evaluated the influence of the renin–angiotensin system (RAS) on intestinal
inflammation and fibrosis. Design Cultured human colonic myofibroblast proliferation and …

ECCO-ESGAR topical review on optimizing reporting for cross-sectional imaging in inflammatory bowel disease

T Kucharzik, J Tielbeek, D Carter… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims The diagnosis and follow up of patients with inflammatory
bowel disease [IBD] requires cross-sectional imaging modalities, such as intestinal …

[BOK][B] Diagnostic ultrasound

CM Rumack, D Levine - 2017 - books.google.com
Now fully updated with more than 2,000 new images and new content throughout,
Diagnostic Ultrasound, 5th Edition, by Drs. Carol M. Rumack and Deborah Levine, remains …

Practical guidelines on endoscopic treatment for Crohn's disease strictures: a consensus statement from the Global Interventional Inflammatory Bowel Disease Group

B Shen, G Kochhar, U Navaneethan… - The lancet …, 2020 - thelancet.com
Stricture formation is a common complication of Crohn's disease, resulting from the disease
process, surgery, or drugs. Endoscopic balloon dilation has an important role in the …

Small bowel Crohn disease at CT and MR enterography: imaging atlas and glossary of terms

FF Guglielmo, SA Anupindi, JG Fletcher… - Radiographics, 2020 - pubs.rsna.org
Representatives from the Society of Abdominal Radiology Crohn's Disease–Focused Panel,
the Society for Pediatric Radiology, the American Gastroenterological Association, and other …