Cancer is a major health issue worldwide, and the global burden of cancer is expected to
increase in the coming years. Whereas the limited success with current therapies has driven …

In industrialized countries, cancer is the second leading cause of death after cardiovascular
disease. Most cancer patients die because of metastases, which consist of the self …

Increasing costs, much time consumption and high risk of failure associated with the process
of de novo development of new anticancer drugs have prompted the pharmaceutical …

Cancer poses a significant global health challenge, with predictions of increasing
prevalence in the coming years due to limited prevention, late diagnosis, and inadequate …

Mitochondria are the cytoplasmic organelles mostly known as the “electric engine” of the
cells; however, they also play pivotal roles in different biological processes, such as cell …

Long Non-Coding RNA (LncRNA) HOXA11-AS Promotes Breast Cancer Invasion and
Metastasis by Regulating Epithelial-Mesenchymal Transition - PMC Back to Top Skip to main …

Background The effect of longer-term use of bone-modifying agent (BMA) on symptomatic
skeletal event (SSE) rates in patients with bone metastases remains unclear. This …

Metastatic spinal tumors (MST) have high rates of morbidity and mortality. MST can destroy
the vertebral body or compress the nerve roots, resulting in an increased risk of pathological …

Proteolytic activity is perturbed in tumors and their microenvironment, and proteases also
affect cancer stem cells (CSCs). CSCs are the therapy-resistant subpopulation of cancer …

Simple Summary The current study was a retrospective exploratory study evaluating
whether circulating levels of known targets of doxycycline were altered following …