The Pseudomonas quinolone signal (PQS) has been studied primarily in the context of its
role as a quorum-sensing signaling molecule. Recent data suggest, however, that this …

Since quinine was first isolated, animals, plants and microorganisms producing a wide
variety of quinolone compounds have been discovered, several of which possess …

Pseudomonas aeruginosa is a metabolically versatile bacterium that is found in a wide
range of biotic and abiotic habitats. It is a major human opportunistic pathogen causing …

Chronic Pseudomonas aeruginosa infections cause significant morbidity in patients with
cystic fibrosis (CF). Over years to decades, P. aeruginosa adapts genetically as it …

Bacteria communicate through the production of diffusible signal molecules termed
autoinducers. The molecules are produced at basal levels and accumulate during growth …

Etiological agents of acute, persistent, or relapsing clinical infections are often refractory to
antibiotics due to multidrug resistance and/or antibiotic tolerance. Pseudomonas aeruginosa …

Pseudomonas aeruginosa is an opportunistic pathogen that produces several virulence
factors such as lectin A, pyocyanin, elastase and rhamnolipids. These compounds are …

Background There are several methods for quantitating bacterial cells, each with
advantages and disadvantages. The most common method is bacterial plating, which has …

The pqs quorum sensing (QS) system is crucial for Pseudomonas aeruginosa virulence both
in vitro and in animal models of infection and is considered an ideal target for the …

Pseudomonas aeruginosa is a leading cause of life-threatening nosocomial infections.
Many virulence factors produced by P. aeruginosa are controlled by the cell-to-cell …