DNAzyme-based dissipative DNA strand displacement for constructing temporal logic gates

M Hu, X Li, J Wu, M Yang, T Wu - Acs Nano, 2024 - ACS Publications
Toehold-mediated DNA strand displacement is the foundation of dynamic DNA
nanotechnology, encompassing a wide range of tools with diverse functions, dynamics, and …

Series or parallel toehold-mediated strand displacement and its application in circular RNA detection and logic gates

S Bai, B Xu, J Wu, G **e - Biosensors and Bioelectronics, 2023 - Elsevier
Toehold-mediated strand displacement (TMSD) is widely employed in constructing a wide
range of chemical reaction networks. In TMSD, single-stranded DNA or RNA can fold back …

Light-controlled growth of DNA organelles in synthetic cells

S Agarwal, M Dizani, D Osmanovic… - Interface …, 2023 - royalsocietypublishing.org
Living cells regulate many of their vital functions through dynamic, membraneless
compartments that phase separate (condense) in response to different types of stimuli. In …

Protein recruitment to dynamic DNA-RNA host condensates

M Dizani, D Sorrentino, S Agarwal… - Journal of the …, 2024 - ACS Publications
We describe the design and characterization of artificial nucleic acid condensates that are
engineered to recruit and locally concentrate proteins of interest in vitro. These condensates …

[HTML][HTML] Fluorescence-Based Multimodal DNA Logic Gates

CH Algama, J Basir, KM Wijesinghe, S Dhakal - Nanomaterials, 2024 - mdpi.com
The use of DNA structures in creating multimodal logic gates bears high potential for
building molecular devices and computation systems. However, due to the complex designs …

DNA nanotechnology in the undergraduate laboratory: Toehold-less strand displacement in switchback DNA

BR Madhanagopal, AR Chandrasekaran - JACS Au, 2024 - ACS Publications
Dynamic DNA nanostructures that reconfigure into different shapes are used in several
applications in biosensing, drug delivery, and data storage. One of the ways to produce such …

A DNA rotary nanodevice operated by enzyme-initiated strand resetting

AR Chandrasekaran - Chemical Communications, 2024 - pubs.rsc.org
DNA nanostructures that respond to external stimuli have found applications in several
areas such as biosensing, drug delivery and molecular computation. The use of different …

GelGenie: an AI-powered framework for gel electrophoresis image analysis

M Aquilina, NJW Wu, K Kwan, F Busic, J Dodd… - bioRxiv, 2024 - biorxiv.org
Gel electrophoresis is a ubiquitous laboratory method for the separation and semi-
quantitative analysis of biomolecules. However, gel image analysis principles have barely …

Designer DNA Strand Displacement Reaction toward Controlled Release of Cargos

CH Hu, R Veneziano - bioRxiv, 2024 - biorxiv.org
Dynamic DNA nanotechnology systems are used to design DNA logic circuits, signal
amplification mechanisms for biosensing, and smart release system that could potentially be …