Engineering therapeutic monoclonal antibodies
CA Stone Jr, BW Spiller, SA Smith - Journal of Allergy and Clinical …, 2024 - Elsevier
The use of human antibodies as biologic therapeutics has revolutionized patient care
throughout fields of medicine. As our understanding of the many roles antibodies play within …
throughout fields of medicine. As our understanding of the many roles antibodies play within …
Virus-like Particles as Vaccines for Allergen-Specific Therapy: An Overview of Current Developments
H Berreiros-Hortala, G Vilchez-Pinto… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Immune engineering and modulation are the basis of a novel but powerful tool to treat
immune diseases using virus-like particles (VLPs). VLPs are formed by the viral capsid …
immune diseases using virus-like particles (VLPs). VLPs are formed by the viral capsid …
Unique allergen-specific human IgE monoclonal antibodies derived from patients with allergic disease
BRE Smith, K Reid Black, M Bermingham, S Agah… - Frontiers in …, 2023 - frontiersin.org
Introduction Allergic reactions are mediated by human IgE antibodies that bind to and cross-
link allergen molecules. The sites on allergens that are recognized by IgE antibodies have …
link allergen molecules. The sites on allergens that are recognized by IgE antibodies have …
Biological activity of human IgE monoclonal antibodies targeting Der p 2, Fel d 1, Ara h 2 in basophil mediator release assays
Background Human Immunoglobulin E monoclonal antibodies (hIgE mAb) are unique tools
for investigating IgE responses. Here, the biological activity of hIgE mAb, derived from …
for investigating IgE responses. Here, the biological activity of hIgE mAb, derived from …
[HTML][HTML] Development and evaluation of mouse anti-Ara h 1 and Ara h 3 IgE monoclonal antibodies for advancing peanut allergy research
T Waritani, S Lomax, D Cutler, J Chang - MethodsX, 2023 - Elsevier
Immediate hypersensitivity reactions to peanuts are a considerable public health concern
due to the acute and severe IgE mediated reactions. To conduct research on the …
due to the acute and severe IgE mediated reactions. To conduct research on the …
Research gaps and future needs for allergen prediction in food safety
A Fernandez, E Danisman, M Taheri Boroujerdi… - Frontiers in …, 2024 - frontiersin.org
The allergenicity and protein risk assessments in food safety are facing new challenges.
Demands for healthier and more sustainable food systems have led to significant advances …
Demands for healthier and more sustainable food systems have led to significant advances …
Molecular allergy diagnosis enabling personalized medicine.
Allergic patients are characterized by complex and patient-specific IgE sensitization profiles
to various allergens, which are accompanied by different phenotypes of allergic disease …
to various allergens, which are accompanied by different phenotypes of allergic disease …
Research gaps and future needs for allergen prediction in food safety
A Fernandez Dumont, E Danisman… - 2024 - digital.csic.es
The allergenicity and protein risk assessments in food safety are facing new challenges.
Demands for healthier and more sustainable food systems have led to significant advances …
Demands for healthier and more sustainable food systems have led to significant advances …