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Obesity paradox: fact or fiction?
Abstract Purpose of Review Obesity is related to several comorbidities such as type 2
diabetes mellitus, cardiovascular disease, heart failure, and various types of cancers. While …
diabetes mellitus, cardiovascular disease, heart failure, and various types of cancers. While …
Global patterns in excess body weight and the associated cancer burden
The prevalence of excess body weight and the associated cancer burden have been rising
over the past several decades globally. Between 1975 and 2016, the prevalence of excess …
over the past several decades globally. Between 1975 and 2016, the prevalence of excess …
Obesity induces PD-1 on macrophages to suppress anti-tumour immunity
Obesity is a leading risk factor for progression and metastasis of many cancers,, yet can in
some cases enhance survival,–and responses to immune checkpoint blockade therapies …
some cases enhance survival,–and responses to immune checkpoint blockade therapies …
Fatty acid metabolism reprogramming in ccRCC: mechanisms and potential targets
Lipid droplet formation is a defining histological feature in clear-cell renal cell carcinoma
(ccRCC) but the underlying mechanisms and importance of this biological behaviour have …
(ccRCC) but the underlying mechanisms and importance of this biological behaviour have …
Epidemiology of renal cell carcinoma: 2022 update
Context International variations in the rates of kidney cancer (KC) are considerable. An
understanding of the risk factors for KC development is necessary to generate opportunities …
understanding of the risk factors for KC development is necessary to generate opportunities …
Association of systemic inflammation index and body mass index with survival in patients with renal cell cancer treated with nivolumab
Purpose: Inflammation indexes and body mass index (BMI) are easily evaluated, predict
survival, and are potentially modifiable. We evaluated the potential association of …
survival, and are potentially modifiable. We evaluated the potential association of …
Towards individualized therapy for metastatic renal cell carcinoma
Over the past decade, the treatment landscape for patients with metastatic renal cell
carcinoma (RCC) has evolved dramatically. The therapeutic options available have …
carcinoma (RCC) has evolved dramatically. The therapeutic options available have …
Trends in renal-cell carcinoma incidence and mortality in the United States in the last 2 decades: a SEER-based study
Background Renal-cell carcinoma (RCC) is one of the common malignancies in the United
States. RCC incidence and mortality have been changing for many reasons. We performed …
States. RCC incidence and mortality have been changing for many reasons. We performed …
Body mass index and metastatic renal cell carcinoma: clinical and biological correlations
L Albiges, AA Hakimi, W ** in obese patients may be more …
An epidemiologic and genomic investigation into the obesity paradox in renal cell carcinoma
Background Obesity increases risk for clear-cell renal cell carcinoma (ccRCC), yet obese
patients appear to experience longer survival than nonobese patients. We examined body …
patients appear to experience longer survival than nonobese patients. We examined body …