Native and bioengineered extracellular vesicles for cardiovascular therapeutics
RC de Abreu, H Fernandes… - Nature reviews …, 2020 - nature.com
Extracellular vesicles (EVs) are a heterogeneous group of natural particles that are relevant
to the treatment of cardiovascular diseases. These endogenous vesicles have certain …
to the treatment of cardiovascular diseases. These endogenous vesicles have certain …
Exosomes and exosome-inspired vesicles for targeted drug delivery
The similarities between exosomes and liposomes, together with the high organotropism of
several types of exosomes, have recently prompted the development of engineered …
several types of exosomes, have recently prompted the development of engineered …
Exosomes—beyond stem cells for restorative therapy in stroke and neurological injury
ZG Zhang, B Buller, M Chopp - Nature Reviews Neurology, 2019 - nature.com
Stroke is a leading cause of disability worldwide, and brain injuries devastate patients and
their families, but currently no drugs on the market promote neurological recovery. Limited …
their families, but currently no drugs on the market promote neurological recovery. Limited …
[HTML][HTML] M2 microglia-derived exosomes protect the mouse brain from ischemia-reperfusion injury via exosomal miR-124
Rationale: Microglia play a critical role in modulating cell death and neurobehavioral
recovery in response to brain injury either by direct cell-cell interaction or indirect secretion …
recovery in response to brain injury either by direct cell-cell interaction or indirect secretion …
Mesenchymal stem cells-derived exosomes for drug delivery
Y Sun, G Liu, K Zhang, Q Cao, T Liu, J Li - Stem cell research & therapy, 2021 - Springer
Exosomes are extracellular vesicles secreted by various cells, mainly composed of lipid
bilayers without organelles. In recent years, an increasing number of researchers have …
bilayers without organelles. In recent years, an increasing number of researchers have …
Exosomes: the next generation of endogenous nanomaterials for advanced drug delivery and therapy
W Liao, Y Du, C Zhang, F Pan, Y Yao, T Zhang, Q Peng - Acta biomaterialia, 2019 - Elsevier
Abstract Development of functional nanomaterials is of great importance and significance for
advanced drug delivery and therapy. Nevertheless, exogenous nanomaterials have a great …
advanced drug delivery and therapy. Nevertheless, exogenous nanomaterials have a great …
Selection of Fluorescent, Bioluminescent, and Radioactive Tracers to Accurately Reflect Extracellular Vesicle Biodistribution in Vivo
The ability to track extracellular vesicles (EVs) in vivo without influencing their biodistribution
is a key requirement for their successful development as drug delivery vehicles and …
is a key requirement for their successful development as drug delivery vehicles and …
Imaging extracellular vesicles: current and emerging methods
STY Chuo, JCY Chien, CPK Lai - Journal of biomedical science, 2018 - Springer
Extracellular vesicles (EVs) are lipid bilayer-enclosed nanoparticles released by cells. They
range from 30 nm to several micrometers in diameter, and ferry biological cargos such as …
range from 30 nm to several micrometers in diameter, and ferry biological cargos such as …
Extracellular vesicles in angiogenesis
D Todorova, S Simoncini, R Lacroix, F Sabatier… - Circulation …, 2017 - Am Heart Assoc
During the past decade, extracellular vesicles (EVs), which include apoptotic bodies,
microvesicles, and exosomes, have emerged as important players in cell-to-cell …
microvesicles, and exosomes, have emerged as important players in cell-to-cell …
Macrophage exosomes as natural nanocarriers for protein delivery to inflamed brain
Recent work has stimulated interest in the use of exosomes as nanocarriers for delivery of
small drugs, RNAs, and proteins to the central nervous system (CNS). To overcome the …
small drugs, RNAs, and proteins to the central nervous system (CNS). To overcome the …