Cancer stem cells: advances in knowledge and implications for cancer therapy
X Chu, W Tian, J Ning, G **ao, Y Zhou… - … and Targeted Therapy, 2024 - nature.com
Cancer stem cells (CSCs), a small subset of cells in tumors that are characterized by self-
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …
renewal and continuous proliferation, lead to tumorigenesis, metastasis, and maintain tumor …
Cancer stem cell functions in hepatocellular carcinoma and comprehensive therapeutic strategies
YC Liu, CT Yeh, KH Lin - Cells, 2020 - mdpi.com
Hepatocellular carcinoma (HCC) is a significant cause of cancer-related mortality owing to
resistance to traditional treatments and tumor recurrence after therapy, which leads to poor …
resistance to traditional treatments and tumor recurrence after therapy, which leads to poor …
Extracellular vesicles and particles impact the systemic landscape of cancer
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy
M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …
Cancer-inducing niche: the force of chronic inflammation
The growth of cancer tissue is thought to be considered driven by a small subpopulation of
cells, so-called cancer stem cells (CSCs). CSCs are located at the apex of a hierarchy in a …
cells, so-called cancer stem cells (CSCs). CSCs are located at the apex of a hierarchy in a …
Conversion of stem cells to cancer stem cells: undercurrent of cancer initiation
Cancer stem cells (CSCs) also known as cancer-initiating cells (CIC), are responsible for the
sustained and uncontrolled growth of malignant tumors and are proposed to play significant …
sustained and uncontrolled growth of malignant tumors and are proposed to play significant …
A cancer stem cell model as the point of origin of cancer-associated fibroblasts in tumor microenvironment
N Nair, AS Calle, MH Zahra, M Prieto-Vila, AKK Oo… - Scientific reports, 2017 - nature.com
Cancer-associated fibroblasts (CAFs) are one of the most prominent cell types in the stromal
compartment of the tumor microenvironment. CAFs support multiple aspects of cancer …
compartment of the tumor microenvironment. CAFs support multiple aspects of cancer …
Dietary sulforaphane in cancer chemoprevention: the role of epigenetic regulation and HDAC inhibition
SM Tortorella, SG Royce, PV Licciardi… - Antioxidants & redox …, 2015 - liebertpub.com
Significance: Sulforaphane, produced by the hydrolytic conversion of glucoraphanin after
ingestion of cruciferous vegetables, particularly broccoli and broccoli sprouts, has been …
ingestion of cruciferous vegetables, particularly broccoli and broccoli sprouts, has been …
Cancer extracellular vesicles, tumoroid models, and tumor microenvironment
Cancer extracellular vesicles (EVs), or exosomes, promote tumor progression through
enhancing tumor growth, initiating epithelial-to-mesenchymal transition, remodeling the …
enhancing tumor growth, initiating epithelial-to-mesenchymal transition, remodeling the …
A novel model of liver cancer stem cells developed from induced pluripotent stem cells
Background Liver cancer is the second most common cause of cancer-related death. Every
type of tumours including liver cancer contains cancer stem cells (CSCs). To date, the …
type of tumours including liver cancer contains cancer stem cells (CSCs). To date, the …