Development and functional diversification of cortical interneurons

L Lim, D Mi, A Llorca, O Marín - Neuron, 2018 - cell.com
In the cerebral cortex, GABAergic interneurons have evolved as a highly heterogeneous
collection of cell types that are characterized by their unique spatial and temporal …

Hippocampal GABAergic inhibitory interneurons

KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

[HTML][HTML] A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain

Z Yao, CTJ van Velthoven, M Kunst, M Zhang… - Nature, 2023 - nature.com
The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties …

[HTML][HTML] Single-cell delineation of lineage and genetic identity in the mouse brain

RC Bandler, I Vitali, RN Delgado, MC Ho… - Nature, 2022 - nature.com
During neurogenesis, mitotic progenitor cells lining the ventricles of the embryonic mouse
brain undergo their final rounds of cell division, giving rise to a wide spectrum of postmitotic …

Mouse and human share conserved transcriptional programs for interneuron development

Y Shi, M Wang, D Mi, T Lu, B Wang, H Dong, S Zhong… - Science, 2021 - science.org
INTRODUCTION The cerebral cortex contains two main classes of neurons that derive from
distinct structures in the develo** telencephalon. Excitatory neurons originate from …

Fused cerebral organoids model interactions between brain regions

JA Bagley, D Reumann, S Bian, J Lévi-Strauss… - Nature …, 2017 - nature.com
Human brain development involves complex interactions between different regions,
including long-distance neuronal migration or formation of major axonal tracts. Different …

Developmental diversification of cortical inhibitory interneurons

C Mayer, C Hafemeister, RC Bandler, R Machold… - Nature, 2018 - nature.com
Diverse subsets of cortical interneurons have vital roles in higher-order brain functions. To
investigate how this diversity is generated, here we used single-cell RNA sequencing to …

[HTML][HTML] The development and evolution of inhibitory neurons in primate cerebrum

MT Schmitz, K Sandoval, CP Chen, MA Mostajo-Radji… - Nature, 2022 - nature.com
Neuroanatomists have long speculated that expanded primate brains contain an increased
morphological diversity of inhibitory neurons (INs), and recent studies have identified …

Interneuron cell types are fit to function

A Kepecs, G Fishell - Nature, 2014 - nature.com
Understanding brain circuits begins with an appreciation of their component parts—the cells.
Although GABAergic interneurons are a minority population within the brain, they are crucial …

A resource of Cre driver lines for genetic targeting of GABAergic neurons in cerebral cortex

H Taniguchi, M He, P Wu, S Kim, R Paik, K Sugino… - Neuron, 2011 - cell.com
A key obstacle to understanding neural circuits in the cerebral cortex is that of unraveling the
diversity of GABAergic interneurons. This diversity poses general questions for neural circuit …