Random DNA barcodes are a versatile tool for tracking cell lineages, with applications
ranging from development to cancer to evolution. Here, we review and critically evaluate …

Improvements in microscopy software and hardware have dramatically increased the pace
of image acquisition, making analysis a major bottleneck in generating quantitative, single …

Synthetic biology aims to engineer biological systems for customized tasks through the
bottom-up assembly of fundamental building blocks, which requires high-quality libraries of …

Plasmids are one of the most commonly used platforms for genetic engineering and
recombinant gene expression in bacteria. The range of available copy numbers for cloning …

Powerful distributed computing can be achieved by communicating cells that individually
perform simple operations. Here, we report design software to divide a large genetic circuit …

It was recently discovered that, depending on their symmetries, collinear antiferromagnets
can actually break the spin degeneracy in momentum space, even in the absence of spin …

Antibiotics are a key control mechanism for synthetic biology and microbiology. Resistance
genes are used to select desired cells and regulate bacterial populations, however their use …

To perform their computational function, genetic circuits change states through a symphony
of genetic parts that turn regulator expression on and off. Debugging is frustrated by an …

Integrons have played a major role in the rise and spread of multidrug resistance in Gram-
negative pathogens and are nowadays commonplace among clinical isolates. These …

To build therapeutic strains, Escherichia coli Nissle (EcN) have been engineered to express
antibiotics, toxin-degrading enzymes, immunoregulators, and anti-cancer chemotherapies …