Immunotherapies have revolutionized the treatment paradigms of various types of cancers.
However, most of these immunomodulatory strategies focus on harnessing adaptive …

Cytokines are critical in regulating immune responses and cellular behavior, playing dual
roles in both normal physiology and the pathology of diseases such as cancer. These …

The advancement of message RNA (mRNA)‐based immunotherapies for cancer is highly
dependent on the effective delivery of RNA (Ribonucleic) payloads using ionizable lipid …

Since the successful application of messenger RNA (mRNA) vaccines in preventing COVID-
19, researchers have been striving to develop mRNA vaccines for clinical use, including …

Summary Interleukin-12 (IL-12) gene transfer enhances the therapeutic potency of adoptive
T cell therapies. We previously reported that transient engineering of tumor-specific CD8 T …

Immunotherapy has become an important part of the oncotherapy arsenal. Its applicability in
various cancer types is impressive, as well as its use of endogenous mechanisms to achieve …

Cells rely on complex molecular networks to perceive and process external and internal
signals into tailored responses. These cellular abilities can be augmented and modified by …

The combination therapy of platinum-based chemotherapy and PD-L1 inhibitors but not the
single anti-PD-L1 therapy has significantly improved the prognosis of patients with small-cell …

In situ vaccination is a desirable strategy for cancer immunotherapy due to its convenience
and capacity to target tumor antigens. Here, an in situ nanovaccine based on a cationic …

Liver diseases have consistently posed substantial challenges to global health. It is crucial
to find innovative methods to effectively prevent and treat these diseases. In recent times …