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[HTML][HTML] Bio-inspired nanomaterials for micro/nanodevices: a new era in biomedical applications
Exploring bio-inspired nanomaterials (BINMs) and incorporating them into
micro/nanodevices represent a significant development in biomedical applications …
micro/nanodevices represent a significant development in biomedical applications …
Learning about liver regeneration from liver-on-a-chip
Liver diseases account for a significant number of deaths worldwide, being largely attributed
to complications of cirrhosis and hepatocellular carcinoma (1). Still, treatment options for …
to complications of cirrhosis and hepatocellular carcinoma (1). Still, treatment options for …
Human induced pluripotent stem cells‐derived liver organoids grown on a Biomimesys® hyaluronic acid‐based hydroscaffold as a new model for studying human …
The liver plays a key role in the metabolism of lipoproteins, controlling both production and
catabolism. To accelerate the development of new lipid‐lowering therapies in humans, it is …
catabolism. To accelerate the development of new lipid‐lowering therapies in humans, it is …
The native liver as inspiration to create superior in vitro hepatic models
Drug induced liver injury (DILI) is one of the major reasons of drug withdrawal during the
different phases of drug development. The later in the drug development a drug is …
different phases of drug development. The later in the drug development a drug is …
Current research trends in the application of in vitro three-dimensional models of liver cells
C Yun, SH Kim, YS Jung - Pharmaceutics, 2022 - mdpi.com
The liver produces and stores various nutrients that are necessary for the body and serves
as a chemical plant, metabolizing carbohydrates, fats, hormones, vitamins, and minerals. It is …
as a chemical plant, metabolizing carbohydrates, fats, hormones, vitamins, and minerals. It is …
Coculture model of a liver sinusoidal endothelial cell barrier and HepG2/C3a spheroids-on-chip in an advanced fluidic platform
The liver is one of the main organs involved in the metabolism of xenobiotics and a key
organ in toxicity studies. Prior to accessing the hepatocytes, xenobiotics pass through the …
organ in toxicity studies. Prior to accessing the hepatocytes, xenobiotics pass through the …
Investigation of the metabolomic crosstalk between liver sinusoidal endothelial cells and hepatocytes exposed to paracetamol using organ-on-chip technology
Organ-on-chip technology is a promising in vitro approach recapitulating human physiology
for the study of responses to drug exposure. Organ-on-chip cell cultures have paved new …
for the study of responses to drug exposure. Organ-on-chip cell cultures have paved new …
A comprehensive review on Bioink based Microfluidic Device
KP Chamate, BD Patil, NV Bhosale, NV Desai… - Bioprinting, 2024 - Elsevier
Microfluidics represents a methodology facilitating the manipulation of minute fluid volumes
via microchannels, with wide-ranging applications across biomedical and pharmaceutical …
via microchannels, with wide-ranging applications across biomedical and pharmaceutical …
[HTML][HTML] Validation of HepG2/C3A cell cultures in cyclic olefin copolymer based microfluidic bioreactors
Organ-on-chip (OoC) technology is one of the most promising in vitro tools to replace the
traditional animal experiment-based paradigms of risk assessment. However, the use of …
traditional animal experiment-based paradigms of risk assessment. However, the use of …
Development of a lung-liver in vitro coculture model for inhalation-like toxicity assessment
Animal models are considered prime study models for inhalation-like toxicity assessment.
However, in light of animal experimentation reduction (3Rs), we developed and investigated …
However, in light of animal experimentation reduction (3Rs), we developed and investigated …