N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation
The ubiquitin-binding endoribonuclease N4BP1 potently suppresses cytokine production by
Toll-like receptors (TLRs) that signal through the adaptor MyD88 but is inactivated via …
Toll-like receptors (TLRs) that signal through the adaptor MyD88 but is inactivated via …
[PDF][PDF] Genetic and biochemical dissection of the ADP-heptose-ALPK1-TIFA innate immune signalling pathway
T Snelling - 2023 - discovery.dundee.ac.uk
At the time I started the experiments described in this thesis, it was already known that ADP-
heptose was an allosteric activator of the kinase activity of ALPK1 and that this led to the …
heptose was an allosteric activator of the kinase activity of ALPK1 and that this led to the …