This overview highlights the emergent area of mechanochemical reactions for making active
pharmaceutical ingredients (APIs), and covers the latest advances in the recently …

Recently, mechanical milling using a mixer mill or planetary mill has been fruitfully utilized in
organic synthesis under solvent-free conditions. This review article provides a …

Mechanochemical approaches in an organic synthesis have received increased interest
because of their wide applications in green methodologies. Ball milling has been fruitfully …

Although known for millennia, it is only recently that mechanochemistry has received serious
attention by chemists. Indeed, during the past 15 years an extraordinary number of reports …

We provide a brief overview of recent advances in the use of mechanochemical techniques
for the synthesis of organic molecules and materials, highlighting selected examples of …

Asymmetric organocatalysis is becoming one of the main tools for the synthesis of chiral
compounds that are needed as medicines, crop protection agents, and other bioactive …

Ball mills input energy to samples by pulverising the contents of the jar. Each impact on the
sample or wall of the jar results in an instantaneous transmission of energy in the form of a …

The past decade has witnessed an explosive growth of interest in mechanochemical
reactions by milling or grinding, and rapid expansion of mechanochemical methodologies …

Chiral α-alkyl α-glycine acids are prevalent structural motifs found in pharmaceuticals and
natural products, making them a significant dimension for exploration in modern …

Mechanochemical activation effectively mediated asymmetric organocatalytic domino
Mannich addition followed by diastereoselective fluorination. The Mannich reactions of …