The intersection between alcohol-related liver disease and nonalcoholic fatty liver disease

LA Díaz, JP Arab, A Louvet, R Bataller… - Nature Reviews …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD) are the
leading causes of chronic liver disease worldwide. NAFLD and ALD share …

Cirrhosis-associated immune dysfunction

A Albillos, R Martin-Mateos, S Van der Merwe… - Nature Reviews …, 2022 - nature.com
The term cirrhosis-associated immune dysfunction (CAID) comprises the distinctive
spectrum of immune alterations associated with the course of end-stage liver disease …

Single-site iron-anchored amyloid hydrogels as catalytic platforms for alcohol detoxification

J Su, P Wang, W Zhou, M Peydayesh, J Zhou… - Nature …, 2024 - nature.com
Constructing effective antidotes to reduce global health impacts induced by alcohol
prevalence is a challenging topic. Despite the positive effects observed with intravenous …

The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

The gut-liver axis in liver disease: Pathophysiological basis for therapy

A Albillos, A De Gottardi, M Rescigno - Journal of hepatology, 2020 - Elsevier
The gut-liver axis refers to the bidirectional relationship between the gut and its microbiota,
and the liver, resulting from the integration of signals generated by dietary, genetic and …

The gut microbiome: a core regulator of metabolism

S Fujisaka, Y Watanabe, K Tobe - Journal of Endocrinology, 2023 - joe.bioscientifica.com
The human body is inhabited by numerous bacteria, fungi, and viruses, and each part has a
unique microbial community structure. The gastrointestinal tract harbors approximately 100 …

Gut microbiome, liver immunology, and liver diseases

R Wang, R Tang, B Li, X Ma, B Schnabl… - Cellular & molecular …, 2021 - nature.com
The gut microbiota is a complex and plastic consortium of microorganisms that are intricately
connected with human physiology. The liver is a central immunological organ that is …

Contribution of the intestinal microbiome and gut barrier to hepatic disorders

DM Chopyk, A Grakoui - Gastroenterology, 2020 - Elsevier
Intestinal barrier dysfunction and dysbiosis contribute to development of diseases in liver
and other organs. Physical, immunologic, and microbiologic (bacterial, fungal, archaeal …

The gut–liver axis and the intersection with the microbiome

A Tripathi, J Debelius, DA Brenner, M Karin… - Nature reviews …, 2018 - nature.com
In the past decade, an exciting realization has been that diverse liver diseases—ranging
from nonalcoholic steatohepatitis, alcoholic steatohepatitis and cirrhosis to hepatocellular …

Alcohol, liver disease and the gut microbiota

JS Bajaj - Nature Reviews Gastroenterology & Hepatology, 2019 - nature.com
Alcoholic liver disease, which ranges from mild disease to alcoholic hepatitis and cirrhosis,
is a leading cause of morbidity and mortality worldwide. Alcohol intake can lead to changes …