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Spatial map** of protein composition and tissue organization: a primer for multiplexed antibody-based imaging
Tissues and organs are composed of distinct cell types that must operate in concert to
perform physiological functions. Efforts to create high-dimensional biomarker catalogs of …
perform physiological functions. Efforts to create high-dimensional biomarker catalogs of …
Spatial metabolomics principles and application to cancer research
M Planque, S Igelmann, AMF Campos… - Current Opinion in …, 2023 - Elsevier
Mass spectrometry imaging (MSI) is an emerging technology in cancer metabolomics.
Desorption electrospray ionization (DESI) and matrix-assisted laser desorption ionization …
Desorption electrospray ionization (DESI) and matrix-assisted laser desorption ionization …
High-performance molecular imaging with MALDI trapped ion-mobility time-of-flight (timsTOF) mass spectrometry
Imaging mass spectrometry (IMS) enables the spatially targeted molecular assessment of
biological tissues at cellular resolutions. New developments and technologies are essential …
biological tissues at cellular resolutions. New developments and technologies are essential …
Image-guided MALDI mass spectrometry for high-throughput single-organelle characterization
DC Castro, YR ** in biology and medicine
EK Neumann, KV Djambazova… - Journal of the …, 2020 - ACS Publications
Imaging mass spectrometry has become a mature molecular map** technology that is
used for molecular discovery in many medical and biological systems. While powerful by …
used for molecular discovery in many medical and biological systems. While powerful by …
Lipid mass tags via aziridination for probing unsaturated lipid isomers and accurate relative quantification
Knowing concentrations of lipids is essential for understanding their physiological functions
and discovering new disease biomarkers. However, it is highly challenging to accurately …
and discovering new disease biomarkers. However, it is highly challenging to accurately …
Mass spectrometry-based single-cell lipidomics: Advancements, challenges, and the path forward
In the past decade, lipidomics, now recognized as standalone subdiscipline of
metabolomics, has gained considerable attention. Due to its sensitivity and unparalleled …
metabolomics, has gained considerable attention. Due to its sensitivity and unparalleled …