Extracellular vesicles secreted by astroglial cells transport apolipoprotein D to neurons and mediate neuronal survival upon oxidative stress

R Pascua-Maestro, E González, C Lillo… - Frontiers in cellular …, 2019 - frontiersin.org
Extracellular vesicle (EV)-mediated glia-to-neuron communication has been recognized in a
growing number of physiological and pathological situations. They transport complex sets of …

Evaluation of Antimicrobial Activity and Cytotoxicity Effects of Extracts of Piper nigrum L. and Piperine

FS Alves, JN Cruz, IN de Farias Ramos… - Separations, 2022 - mdpi.com
P. nigrum L. extracts and the piperine alkaloid have important antimicrobial, anti-
inflammatory, and antioxidant properties. Therefore, in this study, we evaluated the …

Effect of quercetin on dexamethasone-induced C2C12 skeletal muscle cell injury

C Chen, JS Yang, CC Lu, YJ Chiu, HC Chen, MI Chung… - Molecules, 2020 - mdpi.com
Glucocorticoids are widely used anti-inflammatory drugs in clinical settings. However, they
can induce skeletal muscle atrophy by reducing fiber cross-sectional area and myofibrillar …

Synthesis, biological activity, and molecular modelling studies of naphthoquinone derivatives as promising anticancer candidates targeting COX-2

P Kavaliauskas, FS Opazo, W Acevedo, R Petraitiene… - Pharmaceuticals, 2022 - mdpi.com
Non-small cell lung cancer (NSCLC) remains a leading cause of cancer-associated
mortalities worldwide. Therefore, it is crucial to develop a novel therapeutic option targeting …

Ginsenoside Rb1 attenuates high glucose-induced oxidative injury via the NAD-PARP-SIRT axis in rat retinal capillary endothelial cells

C Fan, Q Ma, M Xu, Y Qiao, Y Zhang, P Li, Y Bi… - International Journal of …, 2019 - mdpi.com
(1) Aims: The present study aimed to observe the effects of Ginsenoside Rb1 on high
glucose-induced endothelial damage in rat retinal capillary endothelial cells (RCECs) and to …

Synthesis and bio-activity of complex azo compounds: A review on formazans and its complexes

N Singh, HS Sohal, M Verma, R Sharma… - Main Group …, 2024 - content.iospress.com
Formazans are well-known complexing agents and form highly stable complexes with verity
of metals that are useful for number of pharmaceutical applications. The activity profile of …

Synthesis of biocompatible silver-doped carbonate hydroxyapatite nanoparticles using microwave-assisted precipitation and in vitro studies for the prevention of peri …

S Aziz, ID Ana, Y Yusuf, HD Pranowo - Journal of Functional Biomaterials, 2023 - mdpi.com
A carbonate-hydroxyapatite-based antibacterial implant material with low cytotoxicity was
synthesized. The silver ion (Ag+) was incorporated into CHA material, resulting in silver …

Computational studies and antimicrobial activity of 1-(benzo [d] oxazol-2-yl)-3, 5-diphenylformazan derivatives

M Almehmadi, AA Alsaiari, M Allahyani… - … -Aided Drug Design, 2024 - ingentaconnect.com
Background: Due to the biological importance of the benzoxazole derivatives, some 1-
(benzo [d] oxazol-2-yl)-3, 5-diphenyl-formazans 4a-f were synthesized and screened for in …

PI3Kγ mediates microglial proliferation and cell viability via ROS

C Schmidt, N Schneble-Löhnert, T Lajqi, R Wetzker… - Cells, 2021 - mdpi.com
(1) Background: Rapid microglial proliferation contributes to the complex responses of the
innate immune system in the brain to various neuroinflammatory stimuli. Here, we …

PARP-1 and SIRT-1 are interacted in diabetic nephropathy by activating AMPK/PGC-1α signaling pathway

H Zhu, Z Fang, J Chen, Y Yang, J Gan… - … Syndrome and Obesity, 2021 - Taylor & Francis
Introduction Diabetic nephropathy (DN) is a metabolic disorder characterized by the
accumulation of extracellular matrix (ECM). This study aims to investigate whether exists an …