Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - journals.asm.org
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

Fungal secondary metabolism: regulation, function and drug discovery

NP Keller - Nature Reviews Microbiology, 2019 - nature.com
One of the exciting movements in microbial sciences has been a refocusing and
revitalization of efforts to mine the fungal secondary metabolome. The magnitude of …

Population genomics confirms acquisition of drug-resistant Aspergillus fumigatus infection by humans from the environment

J Rhodes, A Abdolrasouli, K Dunne, TR Sewell… - Nature …, 2022 - nature.com
Infections caused by the fungal pathogen Aspergillus fumigatus are increasingly resistant to
first-line azole antifungal drugs. However, despite its clinical importance, little is known …

How a fungus shapes biotechnology: 100 years of Aspergillus niger research

TC Cairns, C Nai, V Meyer - Fungal biology and biotechnology, 2018 - Springer
In 1917, a food chemist named James Currie made a promising discovery: any strain of the
filamentous mould Aspergillus niger would produce high concentrations of citric acid when …

[PDF][PDF] Ecology of aspergillosis: insights into the pathogenic potency of Aspergillus fumigatus and some other Aspergillus species

C Paulussen, JE Hallsworth… - Microbial …, 2017 - Wiley Online Library
Fungi of the genus Aspergillus are widespread in the environment. Some Aspergillus
species, most commonly Aspergillus fumigatus, may lead to a variety of allergic reactions …

Inhalable Microorganisms in Bei**g's PM2.5 and PM10 Pollutants during a Severe Smog Event

C Cao, W Jiang, B Wang, J Fang, J Lang… - … science & technology, 2014 - ACS Publications
Particulate matter (PM) air pollution poses a formidable public health threat to the city of
Bei**g. Among the various hazards of PM pollutants, microorganisms in PM2. 5 and PM10 …

A comparative genomics study of 23 Aspergillus species from section Flavi

I Kjærbølling, T Vesth, JC Frisvad, JL Nybo… - Nature …, 2020 - nature.com
Section Flavi encompasses both harmful and beneficial Aspergillus species, such as
Aspergillus oryzae, used in food fermentation and enzyme production, and Aspergillus …

A molecular vision of fungal cell wall organization by functional genomics and solid-state NMR

A Chakraborty, LD Fernando, W Fang… - Nature …, 2021 - nature.com
Vast efforts have been devoted to the development of antifungal drugs targeting the cell wall,
but the supramolecular architecture of this carbohydrate-rich composite remains …

antiSMASH 2.0—a versatile platform for genome mining of secondary metabolite producers

K Blin, MH Medema, D Kazempour… - Nucleic acids …, 2013 - academic.oup.com
Microbial secondary metabolites are a potent source of antibiotics and other
pharmaceuticals. Genome mining of their biosynthetic gene clusters has become a key …

2, 5-Diketopiperazines: synthesis, reactions, medicinal chemistry, and bioactive natural products

AD Borthwick - Chemical reviews, 2012 - ACS Publications
2, 5-Diketopiperazines (2, 5-DKPs) are cyclodipeptides obtained by the condensation of two
α-amino acids. They not only abound in nature but are often produced as degradation …