Tissue engineering and regenerative medicine involve many different artificial and biologic
materials, frequently integrated in composite scaffolds, which can be repopulated with …

In the case of pediatric urology there are several congenital conditions, such as
hypospadias and neurogenic bladder, which affect, respectively, the urethra and the urinary …

Organoids are units of function of a given organ able to reproduce, in culture, a biological
structure similar in architecture and function to its counterpart in vivo. Today, it is possible to …

Objective Acellular matrices of different allogeneic or xenogeneic origins are widely used as
structural scaffolds in regenerative medicine. The main goal of this research was to optimize …

Purpose The purpose of this review is to assess the potential role of tissue engineering for
urethral reconstruction. It is well-recognised that urethrotomy remains the first-line therapy in …

Urethral stricture is a common urological disease that seriously affects quality of life.
Urethroplasty with grafts is the primary treatment, but the autografts used in clinical practice …

Hypospadias is a congenital malformation resulting from the disruption of normal urethral
formation with varying global prevalence. Hypospadias repair, especially that of proximal …

Reconstruction for total penile defects presents unique challenges due to its anatomical and
functional complexity. Standard methods suffer from high complication rates and poor …

In recent decades, epidemiological studies have shown a steady increase in the incidence
of disorders in both female and male reproductive system disorders, which can lead to …

The management of neurological disorders heavily relies on neurotherapeutic drugs, but
notable concerns exist regarding their possible negative effects on reproductive health …