Abstract Glycogen synthase kinase‐3 (GSK3) is a highly evolutionarily conserved
serine/threonine protein kinase first identified as an enzyme that regulates glycogen …

Type 2 diabetes mellitus is characterized by the dysregulation of glucose homeostasis,
resulting in hyperglycaemia. Although current diabetes treatments have exhibited some …

In recent years, in-depth studies have shown that extracellular matrix stiffness plays an
important role in cell growth, proliferation, migration, immunity, malignant transformation …

Glycogen synthase kinase 3 (GSK3), a constitutively acting multi‐functional serine threonine
kinase is involved in diverse physiological pathways ranging from metabolism, cell cycle …

Inhibiting glycogen synthase kinase-3 (GSK-3) activity via pharmacological intervention has
become an important strategy for treating neurodegenerative and psychiatric disorders. The …

Neurodegenerative diseases are among the most challenging diseases with poorly known
mechanism of cause and paucity of complete cure. Out of all the neurodegenerative …

Glycogen synthase kinase 3 comprises two isoforms (GSK-3α and GSK-3β) that are
implicated in type II diabetes, neurodegeneration, and cancer. GSK-3 activity is elevated in …

Abstract Glycogen synthase kinase-3 (GSK-3) is a serine/threonine kinase that participates
in an array of critical cellular processes. GSK-3 was first characterized as an enzyme that …

Accumulation of β-amyloid (Aβ) deposits is a primary pathological feature of Alzheimer
disease that is correlated with neurotoxicity and cognitive decline. The role of glycogen …

Dysregulation of the protein kinase glycogen synthase kinase 3 (GSK-3) has been
implicated in the development of type 2 diabetes mellitus. GSK-3 protein expression and …