T follicular helper cell biology: a decade of discovery and diseases
S Crotty - Immunity, 2019 - cell.com
Hel** B cells and antibody responses is a major function of CD4+ T cells. It has been 10
years since the publication of Bcl6 as the lineage-defining transcription factor for T follicular …
years since the publication of Bcl6 as the lineage-defining transcription factor for T follicular …
T cells in health and disease
L Sun, Y Su, A Jiao, X Wang, B Zhang - Signal transduction and …, 2023 - nature.com
T cells are crucial for immune functions to maintain health and prevent disease. T cell
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …
Cytokine regulation and function in T cells
C Dong - Annual review of immunology, 2021 - annualreviews.org
T lymphocytes, the major effector cells in cellular immunity, produce cytokines in immune
responses to mediate inflammation and regulate other types of immune cells. Work in the …
responses to mediate inflammation and regulate other types of immune cells. Work in the …
Selenium–GPX4 axis protects follicular helper T cells from ferroptosis
Follicular helper T (TFH) cells are a specialized subset of CD4+ T cells that essentially
support germinal center responses where high-affinity and long-lived humoral immunity is …
support germinal center responses where high-affinity and long-lived humoral immunity is …
[HTML][HTML] T follicular helper cell differentiation, function, and roles in disease
S Crotty - Immunity, 2014 - cell.com
Follicular helper T (Tfh) cells are specialized providers of T cell help to B cells, and are
essential for germinal center formation, affinity maturation, and the development of most high …
essential for germinal center formation, affinity maturation, and the development of most high …
IgG4-related disease: an update on pathophysiology and implications for clinical care
CA Perugino, JH Stone - Nature Reviews Rheumatology, 2020 - nature.com
Abstract IgG4-related disease (IgG4-RD) has only existed as a unique disease entity since
2003, yet remarkable progress has already been achieved in describing the essential …
2003, yet remarkable progress has already been achieved in describing the essential …
The link between circulating follicular helper T cells and autoimmunity
LSK Walker - Nature Reviews Immunology, 2022 - nature.com
Follicular helper T (TFH) cells provide help to B cells, supporting the formation of germinal
centres that allow affinity maturation of antibody responses. Although usually located in …
centres that allow affinity maturation of antibody responses. Although usually located in …
[HTML][HTML] Time-resolved systems immunology reveals a late juncture linked to fatal COVID-19
COVID-19 exhibits extensive patient-to-patient heterogeneity. To link immune response
variation to disease severity and outcome over time, we longitudinally assessed circulating …
variation to disease severity and outcome over time, we longitudinally assessed circulating …
Memory B cells
T Kurosaki, K Kometani, W Ise - Nature Reviews Immunology, 2015 - nature.com
The immune system can remember a previously experienced pathogen and can evoke an
enhanced response to reinfection that depends on memory lymphocyte populations. Recent …
enhanced response to reinfection that depends on memory lymphocyte populations. Recent …
Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a potentially life-threatening autoimmune disease
characterized by altered balance of activity between effector and regulatory CD4+ T cells …
characterized by altered balance of activity between effector and regulatory CD4+ T cells …