Next generation and other sequencing technologies in diagnostic microbiology and infectious diseases
EE Hilt, P Ferrieri - Genes, 2022 - mdpi.com
Next-generation sequencing (NGS) technologies have become increasingly available for
use in the clinical microbiology diagnostic environment. There are three main applications of …
use in the clinical microbiology diagnostic environment. There are three main applications of …
Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a 2023 TBnet/RESIST-TB consensus statement
J Domínguez, MJ Boeree, E Cambau… - The Lancet Infectious …, 2023 - thelancet.com
Drug-resistant tuberculosis is a substantial health-care concern worldwide. Despite culture-
based methods being considered the gold standard for drug susceptibility testing, molecular …
based methods being considered the gold standard for drug susceptibility testing, molecular …
Investigating resistance in clinical Mycobacterium tuberculosis complex isolates with genomic and phenotypic antimicrobial susceptibility testing: a multicentre …
I Finci, A Albertini, M Merker, S Andres… - The Lancet …, 2022 - thelancet.com
Background Whole-genome sequencing (WGS) of Mycobacterium tuberculosis complex has
become an important tool in diagnosis and management of drug-resistant tuberculosis …
become an important tool in diagnosis and management of drug-resistant tuberculosis …
Evidence-based definition for extensively drug-resistant tuberculosis
M Roelens, G Battista Migliori, L Rozanova… - American journal of …, 2021 - atsjournals.org
Rationale: Until 2020, extensively drug-resistant tuberculosis (XDR-TB) was defined as TB
with resistance to rifampicin and isoniazid (multidrug-resistant TB [MDR-TB]), any …
with resistance to rifampicin and isoniazid (multidrug-resistant TB [MDR-TB]), any …
Drug-resistant tuberculosis: advances in diagnosis and management
Drug-resistant tuberculosis: advances in diagnosis and manag... : Current Opinion in
Pulmonary Medicine Drug-resistant tuberculosis: advances in diagnosis and management …
Pulmonary Medicine Drug-resistant tuberculosis: advances in diagnosis and management …
Performance of a broth microdilution assay for routine minimum inhibitory concentration determination of 14 anti-tuberculous drugs against the Mycobacterium …
M Mansjö, C Espinosa-Gongora… - Antimicrobial Agents …, 2024 - journals.asm.org
This comparative study aimed at qualifying a broth microdilution (BMD) assay for phenotypic
drug susceptibility testing (pDST) of Mycobacterium tuberculosis complex (MTBC) strains for …
drug susceptibility testing (pDST) of Mycobacterium tuberculosis complex (MTBC) strains for …
Emerging bedaquiline-resistant tuberculosis
Tuberculosis is the leading cause of death attributed to a single infectious pathogen
worldwide. Despite the availability of anti-tuberculosis therapies for more than half a century …
worldwide. Despite the availability of anti-tuberculosis therapies for more than half a century …
Evaluating the clinical impact of routine whole genome sequencing in tuberculosis treatment decisions and the issue of isoniazid mono-resistance
M Park, A Lalvani, G Satta, OM Kon - BMC infectious diseases, 2022 - Springer
Background The UK has implemented routine use of whole genome sequencing (WGS) in
TB diagnostics. The WHO recommends addition of a fluoroquinolone for isoniazid mono …
TB diagnostics. The WHO recommends addition of a fluoroquinolone for isoniazid mono …
Clinical standards for drug-susceptible pulmonary TB
OW Akkerman, R Duarte, S Tiberi… - … of Tuberculosis and …, 2022 - ingentaconnect.com
BACKGROUND: The aim of these clinical standards is to provide guidance on 'best practice´
for diagnosis, treatment and management of drug-susceptible pulmonary TB (PTB) …
for diagnosis, treatment and management of drug-susceptible pulmonary TB (PTB) …
Prison as a driver of recent transmissions of multidrug-resistant tuberculosis in Callao, Peru: a cross-sectional study
C Utpatel, M Zavaleta, D Rojas-Bolivar… - The Lancet Regional …, 2024 - thelancet.com
Background We sought to identify resistance patterns and key drivers of recent multidrug-
resistant tuberculosis (MDR-TB) transmission in a TB-prevalent area in Peru. Methods Cross …
resistant tuberculosis (MDR-TB) transmission in a TB-prevalent area in Peru. Methods Cross …