Consensus prediction of cell type labels in single-cell data with popV

C Ergen, G ** the many pathways of IgA induction in the gut
ER Siniscalco, A Williams… - Immunological …, 2024 - Wiley Online Library
The increasing prevalence of food allergy and related pathologies in recent years has
underscored the need to understand the factors affecting adverse reactions to food. Food …

Human γδ T cells in diverse tissues exhibit site-specific maturation dynamics across the life span

JI Gray, DP Caron, SB Wells, R Guyer, P Szabo… - Science …, 2024 - science.org
During ontogeny, γδ T cells emerge from the thymus and directly seed peripheral tissues for
in situ immunity. However, their functional role in humans has largely been defined from …

Maintenance and functional regulation of immune memory to COVID-19 vaccines in tissues

J Davis-Porada, AB George, N Lam, DP Caron, JI Gray… - Immunity, 2024 - cell.com
Memory T and B cells in tissues are essential for protective immunity. Here, we performed a
comprehensive analysis of the tissue distribution, phenotype, durability, and transcriptional …

[HTML][HTML] A heterogeneous pharmaco-transcriptomic landscape induced by targeting a single oncogenic kinase

RM Giglio, N Hou, A Wyatt, J Hong, L Shi… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Over-activation of the epidermal growth factor receptor (EGFR) is a hallmark of glioblastoma.
However, EGFR-targeted therapies have led to minimal clinical response. While delivery of …

ADTnorm: Robust Integration of Single-cell Protein Measurement across CITE-seq Datasets

Y Zheng, DP Caron, JY Kim, SH Jun, Y Tian… - Research …, 2024 - pmc.ncbi.nlm.nih.gov
CITE-seq enables paired measurement of surface protein and mRNA expression in single
cells using antibodies conjugated to oligonucleotide tags. Due to the high copy number of …