Quantifying brain microstructure with diffusion MRI: Theory and parameter estimation

DS Novikov, E Fieremans, SN Jespersen… - NMR in …, 2019 - Wiley Online Library
We review, systematize and discuss models of diffusion in neuronal tissue, by putting them
into an overarching physical context of coarse‐graining over an increasing diffusion length …

[HTML][HTML] Challenges for biophysical modeling of microstructure

IO Jelescu, M Palombo, F Bagnato… - Journal of Neuroscience …, 2020 - Elsevier
The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …

Multiparametric MRI for characterization of the tumour microenvironment

E Hoffmann, M Masthoff, WG Kunz… - Nature Reviews …, 2024 - nature.com
Our understanding of tumour biology has evolved over the past decades and cancer is now
viewed as a complex ecosystem with interactions between various cellular and non-cellular …

Time-dependent diffusion MRI in cancer: tissue modeling and applications

O Reynaud - Frontiers in Physics, 2017 - frontiersin.org
In diffusion weighted imaging (DWI), the apparent diffusion coefficient (ADC) has been
recognized as a useful and sensitive surrogate for cell density, paving the way for non …

Time-dependent diffusion MRI for quantitative microstructural map** of prostate cancer

D Wu, K Jiang, H Li, Z Zhang, R Ba, Y Zhang, YC Hsu… - Radiology, 2022 - pubs.rsna.org
Background Recently developed time-dependent diffusion MRI has potential in
characterizing cellular tissue microstructures; however, its value in imaging prostate cancer …

Magnetic resonance imaging of mean cell size in human breast tumors

J Xu, X Jiang, H Li, LR Arlinghaus… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose Cell size is a fundamental characteristic of all tissues, and changes in cell size in
cancer reflect tumor status and response to treatments, such as apoptosis and cell‐cycle …

Time-dependent diffusion MRI helps predict molecular subtypes and treatment response to neoadjuvant chemotherapy in breast cancer

X Wang, R Ba, Y Huang, Y Cao, H Chen, H Xu, H Shen… - Radiology, 2024 - pubs.rsna.org
Background Time-dependent diffusion MRI has the potential to help characterize tumor cell
properties; however, to the knowledge of the authors, its usefulness for breast cancer …

[HTML][HTML] Imaging brain tumour microstructure

M Nilsson, E Englund, F Szczepankiewicz… - Neuroimage, 2018 - Elsevier
Imaging is an indispensable tool for brain tumour diagnosis, surgical planning, and follow-
up. Definite diagnosis, however, often demands histopathological analysis of microscopic …

Histological and molecular classifications of pediatric glioma with time-dependent diffusion MRI-based microstructural map**

H Zhang, K Liu, R Ba, Z Zhang, Y Zhang… - Neuro …, 2023 - academic.oup.com
Background Gliomas are the most common type of central nervous system tumors in
children, and the combination of histological and molecular classification is essential for …