Bioactive compounds and biomedical applications of endophytic fungi: a recent review

AH Hashem, MS Attia, EK Kandil, MM Fawzi… - Microbial cell …, 2023 - Springer
Human life has been significantly impacted by the creation and spread of novel species of
antibiotic-resistant bacteria and virus strains that are difficult to manage. Scientists and …

[HTML][HTML] Exploring the phytochemicals and anti-cancer potential of the members of Fabaceae family: A comprehensive review

M Usman, WR Khan, N Yousaf, S Akram, G Murtaza… - Molecules, 2022 - mdpi.com
Cancer is the second-ranked disease and a cause of death for millions of people around the
world despite many kinds of available treatments. Phytochemicals are considered a vital …

[HTML][HTML] Proximate composition and health benefit of Roselle leaf (Hibiscus sabdariffa). Insight on food and health benefits

GI Edo, PO Samuel, AN Jikah, GO Oloni… - Food Chemistry …, 2023 - Elsevier
Zobo leaves, also known as Roselle leaves are leaves of the Malvaceae plant Hibiscus
sabdariffa, they are a common culinary ingredient as well as a traditional medicine in many …

Hydrazide-hydrazone/hydrazone as enabling linkers in anti-cancer drug discovery: A comprehensive review

S Murugappan, S Dastari, K Jungare, NM Barve… - Journal of Molecular …, 2024 - Elsevier
The burgeoning demand for novel cytotoxic drugs possessing improved bioavailability and
safety profiles has spurred the hybridization of various pharmacophores in the past decades …

[HTML][HTML] Genkwanin: An emerging natural compound with multifaceted pharmacological effects

N El Menyiy, S Aboulaghras, S Bakrim… - Biomedicine & …, 2023 - Elsevier
Plant bioactive molecules could play key preventive and therapeutic roles in chronological
aging and the pathogenesis of many chronic diseases, often accompanied by increased …

Recent advances in flavonoid-based nanocarriers as an emerging drug delivery approach for cancer chemotherapy

S Dewanjee, P Chakraborty, H Bhattacharya… - Drug Discovery …, 2023 - Elsevier
Highlights•Flavonoids exhibit therapeutic potential against different types of cancer
cells.•Poor pharmacokinetics and biopharmaceutical traits limit their therapeutic …

[HTML][HTML] Polyphenols and their nanoformulations: protective effects against human diseases

S Anand, R Sowbhagya, MA Ansari, MA Alzohairy… - Life, 2022 - mdpi.com
Polyphenols are the secondary metabolites synthesized by the plants as a part of defense
machinery. Owing to their antioxidant, anti-inflammatory, anticancerous, antineoplastic, and …

Flavonoids with anti-angiogenesis function in cancer

Q Wei, Y Zhang - Molecules, 2024 - mdpi.com
The formation of new blood vessels, known as angiogenesis, significantly impacts the
development of multiple types of cancer. Consequently, researchers have focused on …

[HTML][HTML] Apigetrin promotes TNFα-induced apoptosis, necroptosis, G2/M phase cell cycle arrest, and ROS generation through inhibition of NF-κB pathway in Hep3B …

PB Bhosale, A Abusaliya, HH Kim, SE Ha, MY Park… - Cells, 2022 - mdpi.com
Apigetrin (7-(β-D-glucopyranosyloxy)-4′, 5-dihydroxyflavone), a glycoside bioactive dietary
flavonoid derived from Taraxacum officinale and Teucrium gnaphalodes, is known to …

[HTML][HTML] Multi-therapeutic potential of flavonoids as an essential component in nutraceuticals for the treatment and management of human diseases

SIR Okoduwa, I Abdulwaliyu, BE Igiri, SO Arekemase… - Phytomedicine Plus, 2024 - Elsevier
Background Diseases are one of the factors affecting human and national development in
all its ramifications. Some of the diseases that affect humans are usually difficult to manage …