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An inflammation-centric view of neurological disease: beyond the neuron
Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …
Social Safety Theory: Conceptual foundation, underlying mechanisms, and future directions
Classic theories of stress and health are largely based on assumptions regarding how
different psychosocial stressors influence biological processes that, in turn, affect human …
different psychosocial stressors influence biological processes that, in turn, affect human …
The complex aetiology of cerebral palsy
Cerebral palsy (CP) is the most prevalent, severe and costly motor disability of childhood.
Consequently, CP is a public health priority for prevention, but its aetiology has proved …
Consequently, CP is a public health priority for prevention, but its aetiology has proved …
The role of inflammation in perinatal brain injury
Inflammation is increasingly recognized as being a critical contributor to both normal
development and injury outcome in the immature brain. The focus of this Review is to …
development and injury outcome in the immature brain. The focus of this Review is to …
Maternal immune activation and abnormal brain development across CNS disorders
I Knuesel, L Chicha, M Britschgi, SA Schobel… - Nature Reviews …, 2014 - nature.com
Epidemiological studies have shown a clear association between maternal infection and
schizophrenia or autism in the progeny. Animal models have revealed maternal immune …
schizophrenia or autism in the progeny. Animal models have revealed maternal immune …
Long-term risk of neuropsychiatric disease after exposure to infection in utero
Importance The developmental origins of mental illness are incompletely understood.
Although the development of autism and schizophrenia are linked to infections during fetal …
Although the development of autism and schizophrenia are linked to infections during fetal …
Microglia regulate the number of neural precursor cells in the develo** cerebral cortex
Neurogenesis must be properly regulated to ensure that cell production does not exceed the
requirements of the growing cerebral cortex, yet our understanding of mechanisms that …
requirements of the growing cerebral cortex, yet our understanding of mechanisms that …
Neonatal hypoxia ischaemia: mechanisms, models, and therapeutic challenges
Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …
human neonates, and is often associated with persistent motor, sensory, and cognitive …
[HTML][HTML] Brain changes in a maternal immune activation model of neurodevelopmental brain disorders
L Bergdolt, A Dunaevsky - Progress in neurobiology, 2019 - Elsevier
The develo** brain is sensitive to a variety of insults. Epidemiological studies have
identified prenatal exposure to infection as a risk factor for a range of neurological disorders …
identified prenatal exposure to infection as a risk factor for a range of neurological disorders …
Prenatal poly (i: C) exposure and other developmental immune activation models in rodent systems
U Meyer - Biological psychiatry, 2014 - Elsevier
It is increasingly appreciated that altered neuroimmune mechanisms might play a role in the
development of schizophrenia and related psychotic illnesses. On the basis of human …
development of schizophrenia and related psychotic illnesses. On the basis of human …