Characterization of two melanoma cell lines resistant to BRAF/MEK inhibitors (vemurafenib and cobimetinib)
M Kot, A Simiczyjew, J Wądzyńska, M Ziętek… - Cell Communication and …, 2024 - Springer
Background BRAF (v-raf murine sarcoma viral oncogene homolog B1)/MEK (mitogen-
activated protein kinase kinase) inhibitors are used for melanoma treatment. Unfortunately …
activated protein kinase kinase) inhibitors are used for melanoma treatment. Unfortunately …
Computer-aided pattern scoring–A multitarget dataset-driven workflow to predict ligands of orphan targets
The identification of lead molecules and the exploration of novel pharmacological drug
targets are major challenges of medical life sciences today. Genome‐wide association …
targets are major challenges of medical life sciences today. Genome‐wide association …
[HTML][HTML] Co-targeting of DTYMK and PARP1 as a potential therapeutic approach in uveal melanoma
S Oziębło, J Mizera, A Górska, M Krzyziński… - Cells, 2024 - mdpi.com
Uveal melanoma (UM) is the most common primary intraocular tumor in adults, with no
standardized treatment for advanced disease. Based on preliminary bioinformatical …
standardized treatment for advanced disease. Based on preliminary bioinformatical …