Advances in understanding the role of squalene epoxidase in cancer prognosis and resistance
J Zhu, Y Wang, K Zhu, C Zhang - Molecular Biology Reports, 2025 - Springer
Recently, there has been burgeoning interest in the involvement of cholesterol metabolism
in cancer. Squalene epoxidase (SQLE), as a critical rate-limiting enzyme in the cholesterol …
in cancer. Squalene epoxidase (SQLE), as a critical rate-limiting enzyme in the cholesterol …
Advances in predicting breast cancer driver mutations: Tools for precision oncology
W Hao, BK Rajendran, T Cui… - International …, 2024 - spandidos-publications.com
In the modern era of medicine, prognosis and treatment, options for a number of cancer
types including breast cancer have been improved by the identification of cancer-specific …
types including breast cancer have been improved by the identification of cancer-specific …
PI3K Signaling at the Crossroads of Lipid Metabolism and Cancer
S Yilmaz, O Cizmecioglu - 2024 - Springer
The proto-oncogenic PI3K pathway is crucial for the integration of growth factor signaling
and metabolic pathways to facilitate the coordination for cell growth. Since transformed cells …
and metabolic pathways to facilitate the coordination for cell growth. Since transformed cells …
[HTML][HTML] Molecular mechanisms of PI3K isoform dependence in embryonic growth
Objective The phosphoinositide 3-kinase (PI3K) pathway is an important signaling
mechanism for cell proliferation and metabolism. Mutations that activate PIK3CA may make …
mechanism for cell proliferation and metabolism. Mutations that activate PIK3CA may make …