Panax ginseng against myocardial ischemia/reperfusion injury: A review of preclinical evidence and potential mechanisms
J Chen, Q Huang, J Li, Y Yao, W Sun, Z Zhang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Panax ginseng CA Meyer (P. ginseng) is effective in the
prevention and treatment of myocardial ischemia-reperfusion (I/R) injury. The mechanism by …
prevention and treatment of myocardial ischemia-reperfusion (I/R) injury. The mechanism by …
Reactive oxygen species-mediated cardiac-reperfusion injury: mechanisms and therapies
Reperfusion injury is an inherent response to the restoration of blood flow after ischemia. It is
a complex process involving numerous mechanisms occurring in the intracellular and …
a complex process involving numerous mechanisms occurring in the intracellular and …
Attenuation of TNF-α-induced inflammatory injury in endothelial cells by ginsenoside Rb1 via inhibiting NF-κB, JNK and p38 signaling pathways
P Zhou, S Lu, Y Luo, S Wang, K Yang, Y Zhai… - Frontiers in …, 2017 - frontiersin.org
It is currently believed that inflammation plays a central role in the pathophysiology of
atherosclerosis. Oxidative stress and redox-sensitive transcription factors are implicated in …
atherosclerosis. Oxidative stress and redox-sensitive transcription factors are implicated in …
[HTML][HTML] Recent progress (2015–2020) in the investigation of the pharmacological effects and mechanisms of ginsenoside Rb1, a main active ingredient in Panax …
Z Lin, R **e, C Zhong, J Huang, P Shi, H Yao - Journal of ginseng research, 2022 - Elsevier
Abstract Ginsenoside Rb 1 (Rb 1), one of the most important ingredients in Panax ginseng
Meyer, has been confirmed to have favorable activities, including reducing antioxidative …
Meyer, has been confirmed to have favorable activities, including reducing antioxidative …
Inhibition of myocardial cell apoptosis is important mechanism for ginsenoside in the limitation of myocardial ischemia/reperfusion injury
Z Chen, J Wu, S Li, C Liu, Y Ren - Frontiers in Pharmacology, 2022 - frontiersin.org
Ischemic heart disease has a high mortality, and the recommended therapy is reperfusion.
Nevertheless, the restoration of blood flow to ischemic tissue leads to further damage …
Nevertheless, the restoration of blood flow to ischemic tissue leads to further damage …
Ginsenosides for cardiovascular diseases; update on pre-clinical and clinical evidence, pharmacological effects and the mechanisms of action
M Sarhene, JY Ni, ES Duncan, Z Liu, S Li… - Pharmacological …, 2021 - Elsevier
Cardiovascular disease (CVD) remains the major cause of death worldwide, accounting for
almost 31% of the global mortality annually. Several preclinical studies have indicated that …
almost 31% of the global mortality annually. Several preclinical studies have indicated that …
Neuroprotective effects of radix scrophulariae on cerebral ischemia and reperfusion injury via MAPK pathways
X Meng, W **e, Q Xu, T Liang, X Xu, G Sun, X Sun - Molecules, 2018 - mdpi.com
Ischemic stroke is a clinically common cerebrovascular disease whose main risks include
necrosis, apoptosis and cerebral infarction, all caused by cerebral ischemia and reperfusion …
necrosis, apoptosis and cerebral infarction, all caused by cerebral ischemia and reperfusion …
Mitochondrial dysfunction in heart diseases: Potential therapeutic effects of Panax ginseng
X Cao, F Yao, B Zhang, X Sun - Frontiers in Pharmacology, 2023 - frontiersin.org
Heart diseases have a high incidence and mortality rate, and seriously affect people's
quality of life. Mitochondria provide energy for the heart to function properly. The process of …
quality of life. Mitochondria provide energy for the heart to function properly. The process of …
Ginsenoside Rb1 and mitochondria: a short review of the literature
P Zhou, W **e, Y Sun, Z Dai, G Li, G Sun… - Molecular and Cellular …, 2019 - Elsevier
Mitochondria play a central role in various critical cellular processes, including energy
synthesis, energy supply and apoptosis. Panax notoginseng, a commonly used traditional …
synthesis, energy supply and apoptosis. Panax notoginseng, a commonly used traditional …
Inhibitory effects of ginsenoside Rb1 on early atherosclerosis in ApoE-/-mice via inhibition of apoptosis and enhancing autophagy
P Zhou, W **e, Y Luo, S Lu, Z Dai, R Wang, X Zhang… - Molecules, 2018 - mdpi.com
Inflammation is a major contributing factor to the progression of atherosclerosis.
Ginsenoside Rb1 (Rb1), an active saponin of Panax notoginseng, has been found to exert …
Ginsenoside Rb1 (Rb1), an active saponin of Panax notoginseng, has been found to exert …