[HTML][HTML] Multi-omics integration for the design of novel therapies and the identification of novel biomarkers

T Ivanisevic, RN Sewduth - Proteomes, 2023‏ - mdpi.com
Multi-omics is a cutting-edge approach that combines data from different biomolecular
levels, such as DNA, RNA, proteins, metabolites, and epigenetic marks, to obtain a holistic …

Undisclosed, unmet and neglected challenges in multi-omics studies

S Tarazona, A Arzalluz-Luque, A Conesa - Nature Computational …, 2021‏ - nature.com
Multi-omics approaches have become a reality in both large genomics projects and small
laboratories. However, the multi-omics research community still faces a number of issues …

The need for an integrated multi‐OMICs approach in microbiome science in the food system

I Ferrocino, K Rantsiou, R McClure… - … Reviews in Food …, 2023‏ - Wiley Online Library
Microbiome science as an interdisciplinary research field has evolved rapidly over the past
two decades, becoming a popular topic not only in the scientific community and among the …

[HTML][HTML] Big data: historic advances and emerging trends in biomedical research

CJ Cremin, S Dash, X Huang - Current Research in Biotechnology, 2022‏ - Elsevier
Big data is transforming biomedical research by integrating massive amounts of data from
laboratory experiments, clinical investigations, healthcare records, and the internet of things …

[HTML][HTML] Advances in the toxicology research of microcystins based on Omics approaches

Y Ma, H Liu, X Du, Z Shi, X Liu, R Wang, S Zhang… - Environment …, 2021‏ - Elsevier
Microcystins (MCs) are the most widely distributed cyanotoxins, which can be ingested by
animals and human body in multiple ways, resulting in a threat to human health and the …

Invention of 3Mint for feature grou** and scoring in multi-omics

M Unlu Yazici, JS Marron, B Bakir-Gungor, F Zou… - Frontiers in …, 2023‏ - frontiersin.org
Advanced genomic and molecular profiling technologies accelerated the enlightenment of
the regulatory mechanisms behind cancer development and progression, and the targeted …

Coordinated regulation of myonuclear DNA methylation, mRNA, and miRNA levels associates with the metabolic response to rapid synergist ablation-induced skeletal …

A Ismaeel, NT Thomas, M McCashland, IJ Vechetti… - Function, 2024‏ - academic.oup.com
The central dogma of molecular biology dictates the general flow of molecular information
from DNA that leads to a functional cellular outcome. In skeletal muscle fibers, the extent to …

An overview of technologies for MS-based proteomics-centric multi-omics

AT Rajczewski, PD Jagtap, TJ Griffin - Expert review of proteomics, 2022‏ - Taylor & Francis
Introduction Mass spectrometry-based proteomics reveals dynamic molecular signatures
underlying phenotypes reflecting normal and perturbed conditions in living systems …

[HTML][HTML] Multi-omics profiling approach in food allergy

A Devonshire, Y Gautam, E Johansson… - World Allergy …, 2023‏ - Elsevier
The prevalence of food allergy (FA) among children is increasing, affecting nearly 8% of
children, and FA is the most common cause of anaphylaxis and anaphylaxis-related …

[HTML][HTML] Beyond basic diversity estimates—analytical tools for mechanistic interpretations of amplicon sequencing data

A Trego, C Keating, C Nzeteu, A Graham, V O'Flaherty… - Microorganisms, 2022‏ - mdpi.com
Understanding microbial ecology through amplifying short read regions, typically 16S rRNA
for prokaryotic species or 18S rRNA for eukaryotic species, remains a popular, economical …