From shape to function: the next step in bioprinting
Abstract In 2013, the “biofabrication window” was introduced to reflect the processing
challenge for the fields of biofabrication and bioprinting. At that time, the lack of printable …
challenge for the fields of biofabrication and bioprinting. At that time, the lack of printable …
Nanoparticles in tissue engineering: applications, challenges and prospects
Tissue engineering (TE) is an interdisciplinary field integrating engineering, material science
and medical biology that aims to develop biological substitutes to repair, replace, retain, or …
and medical biology that aims to develop biological substitutes to repair, replace, retain, or …
3D self-organized microvascular model of the human blood-brain barrier with endothelial cells, pericytes and astrocytes
The blood-brain barrier (BBB) regulates molecular trafficking, protects against pathogens,
and prevents efficient drug delivery to the brain. Models to date failed to reproduce the …
and prevents efficient drug delivery to the brain. Models to date failed to reproduce the …
Direct 3D bioprinting of perfusable vascular constructs using a blend bioink
Despite the significant technological advancement in tissue engineering, challenges still
exist towards the development of complex and fully functional tissue constructs that mimic …
exist towards the development of complex and fully functional tissue constructs that mimic …
Regenerative medicine: Current therapies and future directions
AS Mao, DJ Mooney - … of the National Academy of Sciences, 2015 - National Acad Sciences
Organ and tissue loss through disease and injury motivate the development of therapies that
can regenerate tissues and decrease reliance on transplantations. Regenerative medicine …
can regenerate tissues and decrease reliance on transplantations. Regenerative medicine …
Self-organizing 3D human neural tissue derived from induced pluripotent stem cells recapitulate Alzheimer's disease phenotypes
The dismal success rate of clinical trials for Alzheimer's disease (AD) motivates us to
develop model systems of AD pathology that have higher predictive validity. The advent of …
develop model systems of AD pathology that have higher predictive validity. The advent of …
Organ-on-a-chip devices advance to market
To curb the high cost of drug development, there is an urgent need to develop more
predictive tissue models using human cells to determine drug efficacy and safety in advance …
predictive tissue models using human cells to determine drug efficacy and safety in advance …
Carbon nanotubes in biomedical applications: factors, mechanisms, and remedies of toxicity: miniperspective
Carbon nanotubes (CNTs) represent one of the most studied allotropes of carbon. The
unique physicochemical properties of CNTs make them among prime candidates for …
unique physicochemical properties of CNTs make them among prime candidates for …
Microphysiological engineering of self-assembled and perfusable microvascular beds for the production of vascularized three-dimensional human microtissues
The vasculature is an essential component of the circulatory system that plays a vital role in
the development, homeostasis, and disease of various organs in the human body. The …
the development, homeostasis, and disease of various organs in the human body. The …
In vitro strategies to vascularize 3D physiologically relevant models
A Dellaquila, C Le Bao, D Letourneur… - Advanced …, 2021 - Wiley Online Library
Vascularization of 3D models represents a major challenge of tissue engineering and a key
prerequisite for their clinical and industrial application. The use of prevascularized models …
prerequisite for their clinical and industrial application. The use of prevascularized models …