The tachykinins, exemplified by substance P, are one of the most intensively studied
neuropeptide families. They comprise a series of structurally related peptides that derive …

This review focuses on the role of the peripheral nervous system in cutaneous biology and
disease. During the last few years, a modern concept of an interactive network between …

Because burn injuries are often followed by a derailed immune response and excessive
inflammation, a thorough understanding of the occurring reactions is key to preventing …

The aim of this article is to furnish a brief review of the role played by neurokinins in the
inflammatory process. Further attention is given to the mechanisms, as well as to the …

Activation of transient receptor potential ankyrin 1 (TRPA1) and vanilloid 1 (TRPV1)
channels on capsaicin-sensitive sensory neurons causes release of inflammatory …

We have used tachykinin neurokinin-1 receptor (NK 1 receptor) knockout mice to learn of the
link between NK 1 receptors and neutrophil accumulation in normal naive skin, as compared …

Neuropeptides play an important role in the active communication between the nervous and
immune systems. Substance P (SP) is a prominent neuropeptide involved in neurogenic …

The problems of itch in burns patients are well recognised, however none of the current
standard therapies are very effective. The standard therapies include: antihistamines which …

Background and purpose: Substance P (SP) and calcitonin gene‐related peptide (CGRP)
released from capsaicin‐sensitive sensory nerves induce local neurogenic inflammation; …

A neurogenic component has been suggested to play a pivotal role in a range of
inflammatory/immune diseases. Mustard oil (allyl-isothiocyanate) has been used in studies …