Breast cancer (BC) is the most common cancer for females and its incidence tends to
increase year by year. Currently, the backbone of therapy for BC is mainly chemotherapy …

The data published mainly over two past decades on various types of biological activity of 5-
functionally substituted 3, 4-dihydropyrimidin-2-ones and their analogues, 2-thiones and 2 …

Abstract A novel series of 4-(1-methyl-1 H-indol-3-yl)-6-(methylthio) pyrimidine-5-
carbonitriles (4a–i) was synthesized and evaluated for anticancer potential against cell lines …

Breast cancer (BC) is the most common cancer for females, and its incidence tends to
increase year by year. Currently, the backbone of therapy for BC is mainly chemotherapy; …

Glucokinase (GK) is a potential therapeutic target of type 2 diabetes and GK activators
(GKAs) represent a promising class of small organic molecules which enhance GK activity …

In the present study a novel Dibenzyl (benzo [d] thiazol-2-yl (hydroxy) methyl) phosphonate
(3b) derived from α-Hydroxyphosphonate exhibited anti-Staphylococcus aureus and anti …

Breast cancer has a rate of occurrence of one in nine. Aromatase also named estrogen
synthase which is found to be associated with breast cancer and it has also been one of the …

A series of diethyl (3-((5-aryl-1H-1, 2, 4-triazol-3-yl) thio) propyl) phos-phonates (7a–t) has
been synthesized in excellent yields by coupling diethyl (3-bromopropyl) phosphonate and …

Breast cancer is one of the leading causes of mortality among women worldwide mostly due
to resistance to existing chemotherapeutic agents. In this study, a bioactive nitro derivative of …

US11780821B2 - Inhibitors of fibroblast activation protein - Google Patents US11780821B2 -
Inhibitors of fibroblast activation protein - Google Patents Inhibitors of fibroblast activation …