Neuroinflammation in acute ischemic and hemorrhagic stroke

DL Alsbrook, M Di Napoli, K Bhatia, J Biller… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review This review aims to provide an overview of neuroinflammation
in ischemic and hemorrhagic stroke, including recent findings on the mechanisms and …

[HTML][HTML] Neuronal injuries in cerebral infarction and ischemic stroke: From mechanisms to treatment

Y Zhao, X Zhang, X Chen… - … journal of molecular …, 2022 - spandidos-publications.com
Stroke is the leading cause of disabilities and cognitive deficits, accounting for 5.2% of all
mortalities worldwide. Transient or permanent occlusion of cerebral vessels leads to …

Rehmannioside A improves cognitive impairment and alleviates ferroptosis via activating PI3K/AKT/Nrf2 and SLC7A11/GPX4 signaling pathway after ischemia

C Fu, Y Wu, S Liu, C Luo, Y Lu, M Liu, L Wang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Rehmannioside A is derived from Rehmannia glutinosa
Libosch, which is widely used as an important ingredient in diverse traditional Chinese …

Pathophysiology of ischemic stroke: role of oxidative stress

S Orellana-Urzúa, I Rojas, L Líbano… - Current …, 2020 - ingentaconnect.com
Stroke is the second leading cause of mortality and the major cause of adult physical
disability worldwide. The currently available treatment to recanalize the blood flow in acute …

The predictive role of systemic inflammation response index (SIRI) in the prognosis of stroke patients

Y Zhang, Z **ng, K Zhou, S Jiang - Clinical interventions in aging, 2021 - Taylor & Francis
Purpose Stroke is a disease associated with high mortality. Many inflammatory indicators
such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte …

The role of miRNAs in insulin resistance and diabetic macrovascular complications–A review

SSA Mageed, AS Doghish, A Ismail… - International journal of …, 2023 - Elsevier
Diabetes is the most prevalent metabolic disturbance disease and has been regarded
globally as one of the principal causes of mortality. Diabetes is accompanied by several …

Mitochondrial dysfunctions induce PANoptosis and ferroptosis in cerebral ischemia/reperfusion injury: from pathology to therapeutic potential

R She, D Liu, J Liao, G Wang, J Ge… - Frontiers in Cellular …, 2023 - frontiersin.org
Ischemic stroke (IS) accounts for more than 80% of the total stroke, which represents the
leading cause of mortality and disability worldwide. Cerebral ischemia/reperfusion injury …

The role of astrocytes in oxidative stress of central nervous system: A mixed blessing

Y Chen, C Qin, J Huang, X Tang, C Liu… - Cell …, 2020 - Wiley Online Library
Central nervous system (CNS) maintains a high level of metabolism, which leads to the
generation of large amounts of free radicals, and it is also one of the most vulnerable organs …

Mitochondria as a therapeutic target for ischemic stroke

Z He, N Ning, Q Zhou, SE Khoshnam… - Free Radical Biology and …, 2020 - Elsevier
Stroke is the leading cause of death and physical disability worldwide. Mitochondrial
dysfunction has been considered as one of the hallmarks of ischemic stroke and contributes …

[HTML][HTML] The role of mitochondrial dynamics in cerebral ischemia-reperfusion injury

J Huang, L Chen, Z Yao, X Sun, X Tong… - Biomedicine & …, 2023 - Elsevier
Stroke is one of the leading causes of death and long-term disability worldwide. More than
80% of strokes are ischemic, caused by an occlusion of cerebral arteries. Without question …