Clarification of vaccines: An overview of filter based technology trends and best practices

L Besnard, V Fabre, M Fettig, E Gousseinov… - Biotechnology …, 2016 - Elsevier
Vaccines are derived from a variety of sources including tissue extracts, bacterial cells, virus
particles, recombinant mammalian, yeast and insect cell produced proteins and nucleic …

Vi capsular polysaccharide: Synthesis, virulence, and application

X Hu, Z Chen, K **ong, J Wang, X Rao… - Critical reviews in …, 2017 - Taylor & Francis
Vi capsular polysaccharide, a linear homopolymer of α-1, 4-linked N-
acetylgalactosaminuronate, is characteristically produced by Salmonella enterica serovar …

Identification of collaborative cross mouse strains permissive to Salmonella enterica serovar Typhi infection

KR Alugupalli, S Kothari, MP Cravens, JA Walker… - Scientific Reports, 2023 - nature.com
Salmonella enterica serovar Typhi is the causative agent of typhoid fever restricted to
humans and does not replicate in commonly used inbred mice. Genetic variation in humans …

Production and purification of an active CRM197 in Pichia pastoris and its immunological characterization using a Vi-typhoid antigen vaccine

R Aw, MR Ashik, AAZM Islam, I Khan, M Mainuddin… - Vaccine, 2021 - Elsevier
CRM197 is a commonly used glycoconjugate carrier that improves the immunogenicity of
vaccines, particularly in infants. Despite the advantages of this diphtheria toxoid mutant, low …

[HTML][HTML] Vaccines, inspiring innovation in health

S Pagliusi, M Dennehy, H Kim… - Vaccine, 2018 - Elsevier
This report covers the topics of pandemics, epidemics and partnerships, including regulatory
convergence initiatives, new technologies and novel vaccines, discussed by leading public …

A new autoclave extract from Anabaena minutissima for seed priming improves tomato plantlets growth and protects against soilborne pathogens

H Righini, S Galletti, S Cianchetta… - Journal of Applied …, 2024 - Springer
This study assessed the effectiveness of the treatment of tomato seeds with an aqueous
extract of the dried biomass of the microalga Anabaena minutissima in protecting the plants …

[HTML][HTML] The lack of natural IgM increases susceptibility and impairs anti-vi polysaccharide IgG responses in a mouse model of typhoid

AS Alugupalli, MP Cravens, JA Walker… - …, 2022 - journals.aai.org
Circulating IgM present in the body prior to any apparent Ag exposure is referred to as
natural IgM. Natural IgM provides protective immunity against a variety of pathogens …

TLR4 ligands in typhoid Vi polysaccharide subunit vaccines contribute to immunogenicity

KR Alugupalli - Immunohorizons, 2024 - journals.aai.org
Activation of B cells and T cells requires the engagement of costimulatory signaling
pathways in addition to Ag receptor signaling for efficient immune responses. None of the …

A TLR4 ligand-based adjuvant for promoting the immunogenicity of Typhoid subunit vaccines

KR Alugupalli - Frontiers in Immunology, 2024 - frontiersin.org
None of the typhoid Vi Polysaccharide (ViPS) subunit vaccines incorporate adjuvants, and
the immunogenicity of ViPS vaccines (eg Typbar TCV® and Typhim Vi®) is in part due to …

Purification of O-specific polysaccharide from lipopolysaccharide produced by Salmonella enterica serovar Paratyphi A

S Kothari, JA Kim, N Kothari, C Jones, WS Choe… - Vaccine, 2014 - Elsevier
The O specific polysaccharide (OSP) of the lipopolysaccharide (LPS) of Salmonella enterica
serovar Paratyphi A is a protective antigen and the target for vaccine development. LPS is …