Advances in numerical simulation of unit operations for tablet preparation

Z Li, WH Peng, WJ Liu, LY Yang, A Naeem… - International Journal of …, 2023 - Elsevier
Recently, there has been an increase in the use of numerical simulation technology in
pharmaceutical preparation processes. Numerical simulation can contribute to a better …

[HTML][HTML] Leveraging Numerical Simulation Technology to Advance Drug Preparation: A Comprehensive Review of Application Scenarios and Cases

Q Gu, H Wu, X Sui, X Zhang, Y Liu, W Feng, R Zhou… - Pharmaceutics, 2024 - mdpi.com
Background/Objectives: Numerical simulation plays an important role in pharmaceutical
preparation recently. Mechanistic models, as a type of numerical model, are widely used in …

Potential effects of inhaler mouthpiece size on particle deposition in the human upper airway

X Cai, B Ma, A Kourmatzis, F Salehi, A Lee… - Aerosol Science and …, 2022 - Taylor & Francis
Understanding the impact of inhaler mouthpiece sizes on particle transport and deposition in
the human upper airway is important to optimize inhaler designs toward improving the …

Effect of Intake position on powder fluidization and conveying characteristics in powder supply device

G Ren, H Sun, Y Xu, C Li, W Shen, Y Cai - Chemical Engineering and …, 2023 - Elsevier
In this work, a novel built-in intake channel powder supply device was developed for the
piston-driven powder fuel feeding system, and a multi-physical coupling model of the gas …

[HTML][HTML] Understanding the effects of inhaler resistance on particle deposition behaviour–A computational modelling study

X Cai, J Dong, L Milton-McGurk, A Lee, Z Shen… - Computers in Biology …, 2023 - Elsevier
Background and objective Understanding the impact of inhaler resistance on particle
transport and deposition in the human upper airway is essential for optimizing inhaler …

Numerical study of dense powder flow in a rotating drum: Comparison of CFD to experimental measurements

L Chatre, X Lemerle, M Bataille, F Herbelet… - Powder Technology, 2024 - Elsevier
Designing chemical reactor equipment requires a thorough understanding of powder flow.
Solid rheology modelling offers various models for this purpose. A comparative study of two …

[HTML][HTML] Numerical investigation of the impact of saber-sheath trachea severity on microparticle deposition in the lower respiratory airway

X Cai, J Dong, K Inthavong, H Gholizadeh… - Journal of Drug Delivery …, 2025 - Elsevier
Understanding the complex mechanisms underpinning the transport and deposition of
aerosols in the human airways is important for improving the effectiveness of oral inhaled …

Numerical simulations and validation of gas–solid flows in a fluidized‐bed roaster based on the CFD‐DPM model

XY Ma, DX Wang, B Liu, H Dong… - The Canadian Journal of …, 2023 - Wiley Online Library
In view of the complex gas–solid flow characteristics in a fluidized‐bed roaster, the discrete
phase model (DPM) provided by ANSYS software was used to numerically analyze the …

Computational fluid dynamics modelling of air entrainment for a plunging jet

F Salehi, E Ajdehak, Y Hardalupas - Chemical Engineering Research and …, 2022 - Elsevier
This study focuses on computational fluid dynamics (CFD) modelling of the air entrainment
phenomena in water columns which are commonly used in processing plants. The CFD …

Revised Bell Particle‐Particle Drag Model of Bicomponent Cohesive Particles in a Fluidized Bed

J Chen, Z Zheng, D Li, Z Zhang, C Zhao… - Chemical …, 2023 - Wiley Online Library
In the framework of the two‐fluid model, the kinetic theory of cohesive particle flow is applied
to bicomponent cohesive particle flow. Based on the Bell particle‐particle drag model, the …