The last decade has seen an increasingly large number of studies reporting on the
development of novel small organic conjugated systems for mitochondrial imaging …

Mitochondrial dysregulation plays a significant role in the carcinogenesis. On the other
hand, its destabilization strongly represses the viability and metastatic potential of cancer …

Triple-negative breast cancer (TNBC) is the most lethal subtype of breast cancer. Hypoxia-
activated prodrugs (HAPs) have shown promise as potential therapeutic agents for TNBC …

In this work, we disclose the new optical property of Cy7-TCF, an asymmetric heptamethine
cyanine in which the indole donor is coupled to the 2-dicyanomethylene-3-cyano-4, 5, 5 …

Lysosomes are essential cellular organelles, serving vital functions in cellular metabolism
and degradation. The design of specifically targeting lysosomes probes with aggregation …

Near-infrared (NIR) cyanine dyes showed enhanced properties for biomedical imaging. A
systematic modification within the cyanine skeleton has been made through a facile design …

In recent years, the studies of RNA and its use for the development of RNA based vaccines
have increased drastically. Although cyanine dyes are commonly used probes for studying …

Owing to its biopenetrability and minimal invasiveness, near-infrared (NIR) light in the region
between 700–1100 nm has attracted attention in cancer diagnosis and therapy. Our group …

The lysosome is an important target for realizing antitumor therapy. Lysosomal cell death
exerts significant therapeutic effects on apoptosis and drug-resistance. The development of …