An overview of infectious bursal disease

HA Mahgoub - Archives of virology, 2012 - Springer
Infectious bursal disease (IBD) is a viral immunosuppressive disease of chickens attacking
mainly an important lymphoid organ in birds [the bursa of Fabricius (BF)]. The emergence of …

The use of nanotechnology in the fight against viruses: A critical review

EK Goharshadi, K Goharshadi, M Moghayedi - Coordination Chemistry …, 2022 - Elsevier
Today, viruses penetrate cells very intelligently with abilities of replicating and disabling the
host's defense mechanisms. The viruses are resistant to conventional treatments mainly due …

A self-amplifying RNA vaccine prevents enterovirus D68 infection and disease in preclinical models

NL Warner, J Archer, S Park, G Singh… - Science translational …, 2024 - science.org
The recent emergence and rapid response to severe acute respiratory syndrome
coronavirus 2 was enabled by prototype pathogen and vaccine platform approaches, driven …

Infectious bursal disease virus in poultry: current status and future prospects

TN Alkie, S Rautenschlein - Veterinary Medicine: Research and …, 2016 - Taylor & Francis
Infectious bursal disease virus (IBDV) affects immature B lymphocytes of the bursa of
Fabricius and may cause significant immunosuppression. It continues to be a leading cause …

DNA vaccination of poultry: the current status in 2015

M Meunier, M Chemaly, D Dory - Vaccine, 2016 - Elsevier
DNA vaccination is a promising alternative strategy for develo** new human and animal
vaccines. The massive efforts made these past 25 years to increase the immunizing …

[HTML][HTML] Co-expression of chicken IL-2 and IL-7 enhances the immunogenicity and protective efficacy of a VP2-expressing DNA vaccine against IBDV in chickens

S Huo, J Zhang, J Fan, X Wang, F Wu, Y Zuo, F Zhong - Viruses, 2019 - mdpi.com
Chicken infectious bursal disease (IBD) is still incompletely controlled worldwide. Although
IBD virus (IBDV) VP2 DNA vaccine was considered a safe vaccine for IBD prevention, the …

Transient expression of VP2 in Nicotiana benthamiana and its use as a plant-based vaccine against infectious bursal disease virus

E Gómez, MS Lucero, SC Zoth, JM Carballeda… - Vaccine, 2013 - Elsevier
Infectious Bursal Disease Virus (IBDV) is the etiological agent of an immunosuppressive and
highly contagious disease that affects young birds. This disease causes important economic …

Designing a bioadjuvant candidate vaccine targeting infectious bursal disease virus (IBDV) using viral VP2 fusion and chicken IL-2 antigenic epitope: a bioinformatics …

S Soleymani, F Janati-Fard… - Computers in Biology and …, 2023 - Elsevier
Abstract Infectious Bursal Disease (IBD) is a common and contagious viral infection that
significantly affects the poultry industry. This severely suppresses the immune system in …

Protection of chicken against very virulent IBDV provided by in ovo priming with DNA vaccine and boosting with killed vaccine and the adjuvant effects of plasmid …

JH Park, HW Sung, BI Yoon… - Journal of veterinary …, 2009 - synapse.koreamed.org
The aim of this study was to examine the efficacy of in ovo prime-boost vaccination against
infectious bursal disease virus (IBDV) using a DNA vaccine to prime in ovo followed by a …

The potent adjuvant effects of chicken β-defensin-1 when genetically fused with infectious bursal disease virus VP2 gene

H Zhang, X Yang, Q **e, J Ma, Y Luo, Y Cao… - Veterinary immunology …, 2010 - Elsevier
Defensins are fundamental components of innate immune response. Current data favor that
defensins play vital roles on both innate and adaptive immune responses. The aim of the …