The phage life cycle is a multi-stage process initiated by the recognition and attachment of
the virus to its bacterial host. This adsorption step depends on the specific interaction …

The biological functions of bacteriophage virions come down to the solution of three basic
problems: to provide protection of viral nucleic acid from the factors of extracellular …

Zinc is a redox-inert trace element that is second only to iron in abundance in biological
systems. In cells, zinc is typically buffered and bound to metalloproteins, but it may also exist …

The emergence of multidrug-resistant bacteria is undoubtedly one of the most serious global
health threats. One response to this threat that has been gaining momentum over the past …

There is a medical need for antibacterial agents that do not damage the resident gut
microbiota or promote the spread of antibiotic resistance. We recently described a prototypic …

The process of a bacteriophage attaching to its host cell is a combination of physical
diffusion, biochemical surface interactions, and reaction-induced conformational changes in …

Surface protein layers (S-layers) often form the only structural component of the archaeal
cell wall and are therefore important for cell survival. S-layers have a plethora of cellular …

Bacillus anthracis, the anthrax agent, is a member of the Bacillus cereus sensu lato group,
which includes invasive pathogens of mammals or insects as well as nonpathogenic …

Lytic bacteriophages (or phages) drive bacterial mortality by elaborating exquisite abilities to
bind, breach, and destroy bacterial cell membranes and subjugate critical bacterial cell …

Anthrax is a highly resilient and deadly disease caused by the spore-forming bacterial
pathogen Bacillus anthracis. The bacterium presents a complex and dynamic composition of …