A review on comparative studies addressing exosome isolation methods from body fluids

TS Martins, M Vaz, AG Henriques - Analytical and Bioanalytical Chemistry, 2023 - Springer
Exosomes emerged as valuable sources of disease biomarkers and new therapeutic tools.
However, extracellular vesicles isolation with exosome-like characteristics from certain …

A guide to mass spectrometric analysis of extracellular vesicle proteins for biomarker discovery

I Jalaludin, DM Lubman, J Kim - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Exosomes (small extracellular vesicles) in living organisms play an important role in
processes such as cell proliferation or intercellular communication. Recently, exosomes …

Magneto-mediated electrochemical sensor for simultaneous analysis of breast cancer exosomal proteins

Y An, R Li, F Zhang, P He - Analytical chemistry, 2020 - ACS Publications
Breast cancer is a heterogeneous disease, and it lacks special tumor markers. Exosomes,
new noninvasive biomarkers, with the proteins on the exosome surface show potential for …

Advances in analytical technologies for extracellular vesicles

H Yan, Y Li, S Cheng, Y Zeng - Analytical Chemistry, 2021 - ACS Publications
Sensitive early detection, along with effective treatments and solid postoperative monitoring
remain the grand challenges in fighting against human diseases, especially cancer.(1) In …

Enhancing clinical potential of liquid biopsy through a multi-omic approach: A systematic review

G Di Sario, V Rossella, ES Famulari, A Maurizio… - Frontiers in …, 2023 - frontiersin.org
In the last years, liquid biopsy gained increasing clinical relevance for detecting and
monitoring several cancer types, being minimally invasive, highly informative and replicable …

Highly efficient exosome purification from human plasma by tangential flow filtration based microfluidic chip

Z Han, C Peng, J Yi, D Zhang, X **ang, X Peng… - Sensors and Actuators B …, 2021 - Elsevier
Exosomes play an important role in microenvironmental regulation, cellular communication,
tumor progression/metastasis and prognosis. A key challenge in the study of exosomes is …

Rolling circle amplification-assisted flow cytometry approach for simultaneous profiling of exosomal surface proteins

X Gao, X Teng, Y Dai, J Li - ACS sensors, 2021 - ACS Publications
Exosomes that carry multiple proteins from the originating cells are known as emerging
biomarkers for tumor diagnostics. However, it is still technically challenging to accurately …

Exploring the versatility of exosomes: a review on isolation, characterization, detection methods, and diverse applications

O Altıntaş, Y Saylan - Analytical Chemistry, 2023 - ACS Publications
Extracellular vesicles (EVs) are crucial mediators of intercellular communication and can be
classified based on their physical properties, biomolecular structure, and origin. Among EVs …

Isolation of platelet-derived exosomes from human platelet-rich plasma: biochemical and morphological characterization

M Saumell-Esnaola, D Delgado… - International Journal of …, 2022 - mdpi.com
Platelet-Rich Plasma (PRP) is enriched in molecular messengers with restorative effects on
altered tissue environments. Upon activation, platelets release a plethora of growth factors …

Analysis of extracellular vesicles as emerging theranostic nanoplatforms

Y **ng, Z Cheng, R Wang, C Lv, TD James… - Coordination Chemistry …, 2020 - Elsevier
Extracellular vesicles (EVs) are nanoscale lipid membrane–bound vesicles that are secreted
by cells of both prokaryotes and eukaryotes and carry bioactive cargos including proteins …