Integrated analysis of transcriptomic and proteomic data
Until recently, understanding the regulatory behavior of cells has been pursued through
independent analysis of the transcriptome or the proteome. Based on the central dogma, it …
independent analysis of the transcriptome or the proteome. Based on the central dogma, it …
Cell biology of diabetic nephropathy: roles of endothelial cells, tubulointerstitial cells and podocytes
Y Maezawa, M Takemoto… - Journal of diabetes …, 2015 - Wiley Online Library
Diabetic nephropathy is the major cause of end‐stage renal failure throughout the world in
both developed and develo** countries. Diabetes affects all cell types of the kidney …
both developed and develo** countries. Diabetes affects all cell types of the kidney …
The single-cell transcriptomic landscape of early human diabetic nephropathy
Diabetic nephropathy is characterized by damage to both the glomerulus and
tubulointerstitium, but relatively little is known about accompanying cell-specific changes in …
tubulointerstitium, but relatively little is known about accompanying cell-specific changes in …
Transcriptome analysis of human diabetic kidney disease
KI Woroniecka, ASD Park, D Mohtat, DB Thomas… - Diabetes, 2011 - Am Diabetes Assoc
OBJECTIVE Diabetic kidney disease (DKD) is the single leading cause of kidney failure in
the US, for which a cure has not yet been found. The aim of our study was to provide an …
the US, for which a cure has not yet been found. The aim of our study was to provide an …
Carnosine as a Protective Factor in Diabetic Nephropathy: Association With a Leucine Repeat of the Carnosinase Gene CNDP1
The risk of diabetic nephropathy is partially genetically determined. Diabetic nephropathy is
linked to a gene locus on chromosome 18q22. 3-q23. We aimed to identify the causative …
linked to a gene locus on chromosome 18q22. 3-q23. We aimed to identify the causative …
Pro-and anti-fibrotic effects of vascular endothelial growth factor in chronic kidney diseases
C Miao, X Zhu, X Wei, M Long, L Jiang, C Li, D **… - Renal failure, 2022 - Taylor & Francis
Renal fibrosis is the inevitable common end-point of all progressive chronic kidney
diseases. The underlying mechanisms of renal fibrosis are complex, and currently there is …
diseases. The underlying mechanisms of renal fibrosis are complex, and currently there is …
Changing landscape of anti-angiogenic therapy: Novel approaches and clinical perspectives
RN Gacche - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Targeting angiogenesis has remained one of the important aspects in disease biology in
general and cancer in particular. Currently (June 2023), over 593 clinical trials have been …
general and cancer in particular. Currently (June 2023), over 593 clinical trials have been …
[HTML][HTML] Fibroblast growth factor 1 ameliorates diabetic nephropathy by an anti-inflammatory mechanism
G Liang, L Song, Z Chen, Y Qian, J **e, L Zhao, Q Lin… - Kidney international, 2018 - Elsevier
Inflammation plays a central role in the etiology of diabetic nephropathy, a global health
issue. We observed a significant reduction in the renal expression of fibroblast growth factor …
issue. We observed a significant reduction in the renal expression of fibroblast growth factor …
Vascular endothelial growth factor and diabetic complications
B Wirostko, TY Wong, R Simó - Progress in retinal and eye research, 2008 - Elsevier
Intraocular delivery of anti-vascular endothelial growth factor (VEGF) therapies is now used
widely to treat age-related macular degeneration, and is currently undergoing evaluation in …
widely to treat age-related macular degeneration, and is currently undergoing evaluation in …
Molecular mechanisms of diabetic vascular complications
M Kitada, Z Zhang, A Mima… - Journal of diabetes …, 2010 - Wiley Online Library
Diabetic complications are the major causes of morbidity and mortality in patients with
diabetes. Microvascular complications include retinopathy, nephropathy and neuropathy …
diabetes. Microvascular complications include retinopathy, nephropathy and neuropathy …