[HTML][HTML] Phytochemicals in drug discovery—A confluence of tradition and innovation

P Chihomvu, A Ganesan, S Gibbons… - International journal of …, 2024 - mdpi.com
Phytochemicals have a long and successful history in drug discovery. With recent
advancements in analytical techniques and methodologies, discovering bioactive leads from …

[HTML][HTML] Initial report on the multiple biological and pharmacological properties of hispolon: Exploring stochastic mechanisms

T Aanniz, I Zeouk, Y Elouafy, J Touhtouh… - Biomedicine & …, 2024 - Elsevier
The development of natural substances derived from nature poses a significant challenge as
technologies for the extraction and characterization of active principles advance. Hispolon …

Simulation screening of umami peptides in the microbiota of soy sauce based on molecular docking and molecular dynamics

Q Wu, C Xu, Y Tian, A Han, Y Liu - Food Bioscience, 2024 - Elsevier
Simulation screening and molecular simulation techniques are gradually being applied to
the study of bioactive peptides. In this study, we explored and simulated the screening …

Molecular docking, in-vitro anticancer evaluation and ADME profiling of 7-Oxo Midostaurin

NS Lakka, C Kuppan, N Vadagam… - Journal of Molecular …, 2023 - Elsevier
Midostaurin drug is used for treatment of acute myeloid leukaemia, myelodysplastic
syndrome, and advanced systemic mastocytosis. Midostaurin under-went oxidation reaction …

New drug discovery

B Yingngam - Multidisciplinary Applications of Natural Science for …, 2023 - igi-global.com
The field of drug discovery is continually advancing with the emergence of new technologies
and scientific developments. Moreover, there is a recent growing interest in exploiting …

Evidence on the inhibitory effect of Brassica plants against Acinetobacter baumannii lipases: phytochemical analysis, in vitro, and molecular docking studies

MM Sabry, AM El-Halawany, WG Fahmy… - … Medicine and Therapies, 2024 - Springer
Abstract Background Infections caused by Acinetobacter baumannii are becoming a rising
public health problem due to its high degree of acquired and intrinsic resistance …

[HTML][HTML] Discovery of multitarget-directed small molecule inhibitors from Andrographis paniculata for Nipah virus disease therapy: Molecular docking, molecular …

M Mandal, S Mandal - Chemical Physics Impact, 2024 - Elsevier
Nipah virus (NiV), an emerging highly infectious agent, causes fatal infection to humans
through zoonosis, particularly in Asian countries including India. No specific treatment or …

Disclosing the functional potency of three oxygenated monoterpenes in combating microbial pathogenesis: from targeting virulence factors to chicken meat …

S Akermi, M Chaari, K Elhadef, M Fourati… - Foods, 2024 - mdpi.com
During the last few decades, there has existed an increased interest in and considerable
consumer preference towards using natural and safe compounds derived from medicinal …

Green synthesis of silver nanoparticles using food supplement from Avena sativa L., and their antioxidant, antiglycation, and anti-aging activities: In vitro and in silico …

BS Bras, I do Nascimento Pereira, LC Zibordi… - Food and Bioproducts …, 2024 - Elsevier
Food supplement of Avena sativa L. dry extract (AsDE) is produced with green leaves of wild
oats and it is commonly used in patients with cognitive disorders and muscle deficits. These …

Assessment of Anticancer Properties of Thai Plants

B Yingngam - Harnessing Medicinal Plants in Cancer Prevention …, 2024 - igi-global.com
Cancer, a critical health concern, necessitates safer, more effective treatments. This chapter
explores the anticancer potential of traditional Thai plants, which, despite being …