A novel anti-osteoporosis mechanism of VK2: interfering with ferroptosis via AMPK/SIRT1 pathway in type 2 diabetic osteoporosis
C **, K Tan, Z Yao, B Lin, D Zhang… - Journal of Agricultural …, 2023 - ACS Publications
Type 2 diabetic osteoporosis (T2DOP) is a chronic bone metabolic disease. Compared with
traditional menopausal osteoporosis, the long-term high glucose (HG) microenvironment …
traditional menopausal osteoporosis, the long-term high glucose (HG) microenvironment …
The role of microbiota-derived vitamins in immune homeostasis and enhancing cancer immunotherapy
Simple Summary Despite clinical success, only a limited percentage of cancer patients are
responsive to immunotherapy. Recently, gut microbiota modulation has been suggested as …
responsive to immunotherapy. Recently, gut microbiota modulation has been suggested as …
Biofilm reactors as a promising method for vitamin K (menaquinone-7) production
Abstract Menaquinone-7 (MK-7) is the most potent subtype of vitamin K with extraordinarily
high half-life in the circulatory system. Therefore, MK-7 plays a critical role in promoting …
high half-life in the circulatory system. Therefore, MK-7 plays a critical role in promoting …
Metal nanoparticle alters adenine induced charge transfer kinetics of vitamin K3 in magnetic field
In this article, we highlight the alterations in the photoinduced electron transfer (ET) and
hydrogen atom transfer (HAT) pathways between an anti-tumor drug vitamin-K3 (MQ) and a …
hydrogen atom transfer (HAT) pathways between an anti-tumor drug vitamin-K3 (MQ) and a …
UBIAD1 suppresses the proliferation of bladder carcinoma cells by regulating H-Ras intracellular trafficking via interaction with the C-terminal domain of H-Ras
Z Xu, F Duan, H Lu, M Abdulkadhim Dragh, Y **a… - Cell Death & …, 2018 - nature.com
UbiA prenyltransferase domain-containing protein 1 (UBIAD1) plays a key role in
biosynthesis of vitamin K2 and coenzyme Q10 using geranylgeranyl diphosphate (GGPP) …
biosynthesis of vitamin K2 and coenzyme Q10 using geranylgeranyl diphosphate (GGPP) …
Vitamin K2 enhances the tumor suppressive effects of 1, 25 (OH) 2D3 in triple negative breast cancer cells
K vitamins are well known as essential cofactors for hepatic γ-carboxylation of coagulation
factors, but their potential role in chronic diseases including cancer is understudied. K2, the …
factors, but their potential role in chronic diseases including cancer is understudied. K2, the …
A simple and efficient preparative procedure for menaquinone-7 from Bacillus subtilis (natto) using two-stage extraction followed by microporous resins
Z Fang, L Wang, G Zhao, H Liu, H Wei, H Wang… - Process …, 2019 - Elsevier
Abstract Meanquinone-7 (MK-7) can be produced by the fermentation of Bacillus subtilis
(natto), which is known for its nutraceutical and pharmacological properties. This study …
(natto), which is known for its nutraceutical and pharmacological properties. This study …
Evaluating Risk: Benefit Ratio of Fat-Soluble Vitamin Supplementation to SARS-CoV-2-Infected Autoimmune and Cancer Patients: Do Vitamin–Drug Interactions Exist …
Simple Summary This review brings attention to a crucial yet under-investigated subject
which is vitamin–drug interactions. Fat-soluble vitamins such as vitamins A, D, E, and K have …
which is vitamin–drug interactions. Fat-soluble vitamins such as vitamins A, D, E, and K have …
Synthesis and characterization of partially and fully saturated menaquinone derivatives
Menaquinones (MKs) contain both a redox active quinone moiety and a hydrophobic
repeating isoprenyl side chain of varying lengths and degrees of saturation. This …
repeating isoprenyl side chain of varying lengths and degrees of saturation. This …
[HTML][HTML] Fruit fly for anticancer drug discovery and repurposing
In 2020, around one of six deaths was attributed to cancer-related diseases, making cancer
as one of the leading causes of mortality worldwide 1. Cancer is a complex multifaceted …
as one of the leading causes of mortality worldwide 1. Cancer is a complex multifaceted …