The nuclear-to-cytoplasmic ratio: coupling DNA content to cell size, cell cycle, and biosynthetic capacity

S Balachandra, S Sarkar… - Annual review of genetics, 2022 - annualreviews.org
Though cell size varies between different cells and across species, the nuclear-to-
cytoplasmic (N/C) ratio is largely maintained across species and within cell types. A cell …

How metabolic rate relates to cell size

DS Glazier - Biology, 2022 - mdpi.com
Simple Summary The metabolic conversion of resources into living structures and processes
is fundamental to all living systems. The rate of metabolism ('fire of life') is critical for …

Convergent evolution toward a slow pace of life predisposes insular endotherms to anthropogenic extinctions

Y **ong, R Rozzi, Y Zhang, L Fan, J Zhao, D Li… - Science …, 2024 - science.org
Island vertebrates have evolved a number of morphological, physiological, and life history
characteristics that set them apart from their mainland relatives. However, to date, the …

Diverse aging rates in ectothermic tetrapods provide insights for the evolution of aging and longevity

BA Reinke, H Cayuela, FJ Janzen, JF Lemaître… - Science, 2022 - science.org
Comparative studies of mortality in the wild are necessary to understand the evolution of
aging; yet, ectothermic tetrapods are underrepresented in this comparative landscape …

The evolution of mechanisms involved in vertebrate endothermy

LJ Legendre, D Davesne - Philosophical Transactions of …, 2020 - royalsocietypublishing.org
Endothermy, ie the endogenous production of metabolic heat, has evolved multiple times
among vertebrates, and several strategies of heat production have been studied extensively …

Polyploidy in Xenopus lowers metabolic rate by decreasing total cell surface area

C Cadart, J Bartz, G Oaks, MZ Liu, R Heald - Current Biology, 2023 - cell.com
Although polyploidization is frequent in development, cancer, and evolution, impacts on
animal metabolism are poorly understood. In Xenopus frogs, the number of genome copies …

Scaling of biosynthesis and metabolism with cell size

C Cadart, R Heald - Molecular Biology of the Cell, 2022 - Am Soc Cell Biol
Cells adopt a size that is optimal for their function, and pushing them beyond this limit can
cause cell aging and death by senescence or reduce proliferative potential. However, by …

Tetrapod sperm length evolution in relation to body mass is shaped by multiple trade-offs

L Koçillari, S Cattelan, MB Rasotto, F Seno… - Nature …, 2024 - nature.com
Sperm length is highly variable across species and many questions about its variation
remain open. Although variation in body mass may affect sperm length evolution through its …

ModEst: Accurate estimation of genome size from next generation sequencing data

M Pfenninger, P Schönnenbeck… - Molecular ecology …, 2022 - Wiley Online Library
Accurate estimates of genome sizes are important parameters for both theoretical and
practical biodiversity genomics. Here we present a fast, easy‐to‐implement and accurate …

Integrative paleophysiology of the metriorhynchoid Pelagosaurus typus (Pseudosuchia, Thalattosuchia)

J Cubo, MVA Sena, R Pellarin… - The Anatomical …, 2025 - Wiley Online Library
Paleophysiology is an emergent discipline. Organismic (integrative) approaches seem more
appropriate than studies focusing on the variation of specific features because traits are …