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[HTML][HTML] Heterocyclic anticancer compounds: recent advances and the paradigm shift towards the use of nanomedicine's tool box
The majority of heterocycle compounds and typically common heterocycle fragments
present in most pharmaceuticals currently marketed, alongside with their intrinsic versatility …
present in most pharmaceuticals currently marketed, alongside with their intrinsic versatility …
Comprehensive review in current developments of benzimidazole‐based medicinal chemistry
The properties of benzimidazole and its derivatives have been studied over more than one
hundred years. Benzimidazole derivatives are useful intermediates/subunits for the …
hundred years. Benzimidazole derivatives are useful intermediates/subunits for the …
Acid hydrazides, potent reagents for synthesis of oxygen-, nitrogen-, and/or sulfur-containing heterocyclic rings
Heterocycles form by far the largest of the classical divisions of organic chemistry. Moreover,
they are of immense importance not only both biologically and industrially but also to the …
they are of immense importance not only both biologically and industrially but also to the …
Therapeutic evolution of benzimidazole derivatives in the last quinquennial period
Benzimidazole, a fused heterocycle bearing benzene and imidazole has gained
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …
considerable attention in the field of contemporary medicinal chemistry. The moiety is of …
[HTML][HTML] Benzimidazole-triazole hybrids as antimicrobial and antiviral agents: A systematic review
M Marinescu - Antibiotics, 2023 - mdpi.com
Bacterial infections have attracted the attention of researchers in recent decades, especially
due to the special problems they have faced, such as their increasing diversity and …
due to the special problems they have faced, such as their increasing diversity and …
[HTML][HTML] Benzimidazole: A versatile scaffold for drug discovery and beyond–A comprehensive review of synthetic approaches and recent advancements in medicinal …
Heterocyclic compounds are foundational in drug discovery, constituting the core structure of
approximately 80% of pharmaceuticals. Benzimidazole, in particular, emerges as a critical …
approximately 80% of pharmaceuticals. Benzimidazole, in particular, emerges as a critical …
Recent developments on 1, 2, 4-triazole nucleus in anticancer compounds: a review
1, 2, 4-triazole is an important nucleus present in a large number of compounds. More than
thirty-five compounds containing this nucleus are introduced into the market. 1, 2, 4-triazole …
thirty-five compounds containing this nucleus are introduced into the market. 1, 2, 4-triazole …
Anti-cancer nitrogen-containing heterocyclic compounds
Cancer is one of the leading causes of death worldwide. Mutation of the cell regulates genes
and protein causing cancer. Surgery, radiotherapy, and the use of anticancer agents are the …
and protein causing cancer. Surgery, radiotherapy, and the use of anticancer agents are the …
Benzimidazole scaffold as anticancer agent: synthetic approaches and structure–activity relationship
Cancer, also known as malignant neoplasm, is a dreadful disease which involves abnormal
cell growth having the potential to invade or spread to other parts of the body …
cell growth having the potential to invade or spread to other parts of the body …
Benzotriazole: An overview on its versatile biological behavior
I Briguglio, S Piras, P Corona, E Gavini… - European Journal of …, 2015 - Elsevier
Discovered in late 1960, azoles are heterocyclic compounds class which constitute the
largest group of available antifungal drugs. Particularly, the imidazole ring is the chemical …
largest group of available antifungal drugs. Particularly, the imidazole ring is the chemical …