AGA clinical practice update on de-prescribing of proton pump inhibitors: expert review

LE Targownik, DA Fisher, SD Saini - Gastroenterology, 2022 - Elsevier
Description Proton pump inhibitors (PPIs) are among the most commonly used medications
in the world. Developed for the treatment and prevention of acid-mediated upper …

Gastroesophageal reflux disease: a review

J Maret-Ouda, SR Markar, J Lagergren - Jama, 2020 - jamanetwork.com
Importance Gastroesophageal reflux disease (GERD) is defined by recurrent and
troublesome heartburn and regurgitation or GERD-specific complications and affects …

Diagnosis and management of Barrett's esophagus: an updated ACG guideline

NJ Shaheen, GW Falk, PG Iyer, RF Souza… - Official journal of the …, 2022 - journals.lww.com
Barrett's esophagus (BE) is a common condition associated with chronic gastroesophageal
reflux disease. BE is the only known precursor to esophageal adenocarcinoma, a highly …

Accuracy of the PHQ-2 alone and in combination with the PHQ-9 for screening to detect major depression: systematic review and meta-analysis

B Levis, Y Sun, C He, Y Wu, A Krishnan, PM Bhandari… - Jama, 2020 - jamanetwork.com
Importance The Patient Health Questionnaire depression module (PHQ-9) is a 9-item self-
administered instrument used for detecting depression and assessing severity of …

Global burden and epidemiology of Barrett oesophagus and oesophageal cancer

AP Thrift - Nature reviews Gastroenterology & hepatology, 2021 - nature.com
Oesophageal cancer is a global health problem; in 2018 there were more than 572,000
people newly diagnosed with oesophageal cancer worldwide. There are two main …

Impact of risk factors on early cancer evolution

CE Weeden, W Hill, EL Lim, E Grönroos, C Swanton - Cell, 2023 - cell.com
Recent identification of oncogenic cells within healthy tissues and the prevalence of indolent
cancers found incidentally at autopsies reveal a greater complexity in tumor initiation than …

Current status and future prospects for esophageal cancer

M Sheikh, G Roshandel, V McCormack, R Malekzadeh - Cancers, 2023 - mdpi.com
Simple Summary Over 500,000 individuals died due to esophageal cancer (EC) worldwide
in 2020. More than four decades of etiological research have predominantly focused on the …

Safety of proton pump inhibitors based on a large, multi-year, randomized trial of patients receiving rivaroxaban or aspirin

P Moayyedi, JW Eikelboom, J Bosch, SJ Connolly… - Gastroenterology, 2019 - Elsevier
Background & Aims Proton pump inhibitors (PPIs) are effective at treating acid-related
disorders. These drugs are well tolerated in the short term, but long-term treatment was …

ASGE guideline on screening and surveillance of Barrett's esophagus

B Qumseya, S Sultan, P Bain, L Jamil… - Gastrointestinal …, 2019 - giejournal.org
This document is the official American Society for Gastrointestinal Endoscopy guideline on
screening and surveillance in patients with Barrett's esophagus (BE) and is based on …

Advances in the diagnosis and management of gastroesophageal reflux disease

DA Katzka, PJ Kahrilas - Bmj, 2020 - bmj.com
Gastroesophageal reflux disease (GERD) is a multifaceted disorder encompassing a family
of syndromes attributable to, or exacerbated by, gastroesophageal reflux that impart …